NFL | Jacksonville 31 @ Indianapolis 21 | 09/10 | 5:00 PM UTC
Jacksonville -4.5 -110
ANALYSIS: Rookie head coach? Rookie QB? Going up a team that is trending in the right direction, with a MVP caliber QB? I don't really care that the Colts have failed to win a week 1 game in the previous 8 seasons, but they are going to have to wait until 2024 to break that streak. Trevor Lawrence and the Jaguars should be able to take care of business and cover the 4.5 points in Indy.