ANALYSIS: Will the Twins avoid a third straight loss? ... Join SportsLine here to see the full pick!

ANALYSIS: Join SportsLine here to see the full pick!

ANALYSIS: The Bucs are getting healthier. ... Join SportsLine here to see the full pick!

ANALYSIS: The 49ers' offense looks dreadful. ... Join SportsLine here to see the full pick!

ANALYSIS: It’s gut check time for the Mets. If they win tonight, they are tied in the standings with the Braves but own the tiebreaker. If they lose, the Braves go up 2 games in the division and they own the tiebreaker with 3 games left. I think the Mets pull through and win this game and stay in control of their own destiny to win the NL East.

ANALYSIS: The Broncos are inching up to getting a full field goal ahead of kickoff, but we’re running out of time. Though neither team has impressed early in the season, the Raiders are completely out of sorts. Derek Carr will be the best quarterback that the Broncos have faced at this early juncture – their defense has feasted on far worse offenses than Las Vegas’ – but without Hunter Renfrow, it’s tough to see the hosts finding enough consistency through four quarters. Denver, meanwhile, seemed to finally put things together in the fourth quarter against San Francisco last week and could easily win this outright. This will be a half-bet for me at +2.5 (+100), but I'd go with a whole wager at +3 (-110) if you can get it.

ANALYSIS: Here's four people I do not trust: Kyler Murray, Baker Mayfield, Kliff Kingsbury and Matt Rhule. It’s problematic that all will have significant roles in this game, yet, there’s no doubt that Murray has been far superior to Mayfield, arguably the worst starter in the NFL this season. The Cardinals are getting James Conner back healthy with Marquise Brown and Rondale Moore both playing. Arizona also plays well historically as a road underdog with Kingsbury leading the charge. Christian McCaffrey is back for the Panthers, but it’s not enough to get me to side with the home team.

ANALYSIS: If the Packers were playing a generic team with the same statistics as their actual opponent Sunday, Green Bay might be a 12-point home favorite. The Patriots and Bill Belichick are receiving a benefit of the doubt here that they do not deserve. As creative as Belichick has been when dealing with obstacles in the past, those teams were at least good; this one is not. The Pats' lone win this season was by three against dreadful Steelers team. Against teams with actual offenses, they've lost by 13 and 11. And now they see a Packers team with a legitimate homefield advantage and the best running game and defense they've seen so far this season. Oh yeah, and Aaron Rodgers is playing. I'm not concerned about Green Bay's lacking pass catchers; it should have more than enough to win by double digits.

ANALYSIS: Two banged-up defenses meet in a second straight tough road game for the Bills coming off their loss to the Dolphins last week. The Ravens were able to bounce back from their own Dolphins loss to find some answers on both sides of the ball against the Patriots, but it will be tough for Buffalo to do the same against a team that has the offensive weaponry to keep the visitors on their toes. The weather is also an issue here, which makes the field goal incredibly valuable. The hope in waiting to pick was that the Ravens would get the hook before kickoff; that may still happen -- +3.5 (-110) would be preferred -- but +3 (+100) is great value for the home team in a better spot with a quarterback in Lamar Jackson who appears to be on an MVP track.

ANALYSIS: It’s difficult enough to play the Steelers. Doing so in Pittsburgh as a quarterback in his first action of the season is particularly rough. The Jets present an opportunity for the Steelers to finally move the ball offensively, and if Pittsburgh is willing to use Jaylen Warren to spell Najee Harris more frequently, it could be a breakout effort for the running game. Mike Tomlin also had extra time to prepare, and I do prefer to side with the Steelers in potentially ugly football games with a spread sitting around or inside a field goal. Pittsburgh should be favored by 4.5-5 in this game.

ANALYSIS: When you consider the Cowboys were an underdog last week to the Giants, it's clear this line is a significant market adjustment for Dallas. And yet, it is still the right side going against a Washington team that cannot protect its quarterback and appears headed towards a top five pick in next year's NFL Draft. Cooper Rush is playing well enough in a game manager role, but its the Cowboys running game and defense that gets me excited about this spread. Try to avoid the forthcoming hook if possible. It's worth taking the 'Boys up to -3 (-120).

ANALYSIS: Although many bettors seem willing to lay double figures in points with the Packers, this might not be quite the mismatch it appears at first glance. Green Bay still has limited weapons in the passing game, and the Patriots defense will be determined to stop the run and force long down and distance. New England will use its own run-powered drives to shorten the game and limit possessions. New England outgained Baltimore in a loss last week and held Miami's potent offense to 13 points in the opener (7 came on a defensive TD). Look for an ugly punt-filled festival that ends in a one-score game.