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    Sun, Sep 105:00 pm UTCAcrisure Stadium
    73 F
    Track OnCBS Sports
    San Francisco
    49ers
    SF
    Last 5 ATS
    W/L9-3
    ATS7-5
    O/U5-6-1
    FINAL SCORE
    30
    -
    7
    Pittsburgh
    Steelers
    PIT
    Last 5 ATS
    W/L7-5
    ATS7-5
    O/U10-2-0
    SPREAD
    MONEYLINE
    OVER/UNDER
    Last 5 ATS
    9-3
    Win /Loss
    7-5
    7-5
    Spread
    7-5
    5-6-1
    Over / Under
    10-2-0
    Key Injuries
    Key Injuries
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    WR
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    TE
    Key Injuries
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    OG
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    OLB
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    C
    SPREAD
    MONEYLINE
    OVER/UNDER

    Simulation Picks

    SPREAD
    SF @ PIT
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    MONEYLINE
    SF @ PIT
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    OVER / UNDER
    SF @ PIT
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    0%
    PUBLIC
    0%
    MONEY
    0%
    PUBLIC
    0%
    MONEY
    Over0%
    PUBLIC
    Under0%
    Over
    MONEY
    Under

    Expert Picks

    Point SpreadPittsburgh +2 -110
    LOSS
    Unit1.0
    +2699
    59-29-6 in Last 94 NFL ATS Picks
    +726
    25-16-1 in Last 42 PIT ATS Picks
    Adam's Analysis:

    There’s no doubt that the 49ers are one of the best teams in the NFL, and it’s great for San Francisco that Nick Bosa is back in the fold. But let’s not forget that T.J. Watt is back for the Steelers, an immensely well-coached team with Kenny Pickett growing in confidence this offseason entering his second year as a starter with a better run game helping him offensively. I expect San Fran’s defense to take a half step back with coordinator and personnel changes, and in what I anticipate being a low-scoring game, taking the points with the home team against a West Coast opponent makes a lot of sense.

    Pick Made: Sep 10, 4:33 pm UTC
    Point SpreadSan Francisco -2 -110
    WIN
    Unit1.0
    +1118
    36-21-1 in Last 58 NFL Picks
    +359
    8-4-1 in Last 13 NFL ATS Picks
    +500
    5-0 in Last 5 SF ATS Picks
    Sia's Analysis:

    The 49ers are easily one of the top 2 teams in the NFC and I'm not going to overthink this pick against an allegedly emerging Steelers team. The Steelers are solid all around, but they are not in the class of the 49ers. Yes, Brock Purdy does worry me a bit, but I'm fully confident that Kyle Shanahan will give him plenty of opportunities to find his elite pass catchers in space.

    Pick Made: Sep 10, 2:32 pm UTC
    Money LineSan Francisco -135
    WIN
    Unit1.0
    +1574.5
    47-28-4 in Last 79 NFL Picks
    +575
    7-1 in Last 8 NFL ML Picks
    +90
    2-1 in Last 3 PIT ML Picks
    Josh's Analysis:

    Although the Steelers should be improved, the 49ers are coming off a run to the NFC championship game and could easily be headed toward another. This line is a shade just too light.

    Pick Made: Sep 10, 2:15 pm UTC
    PropChristian McCaffrey Anytime Touchdown Scorer -110
    WIN
    Unit0.5
    Matt's Analysis:

    Must I even explain? Fully expect a rather conservative gameplan for the Niners with QB Brock Purdy having missed so much time this offseason rehabbing from surgery and against a stellar defense. McCaffrey could get 25+ touches between rushing and receiving. Including playoffs, he has scored a TD in nine straight games.

    Pick Made: Sep 08, 2:55 pm UTC
    Over / UnderUNDER 41 -110
    WIN
    Unit1.0
    +1162.5
    50-31-1 in Last 82 NFL Picks
    +300
    3-0 in Last 3 NFL O/U Picks
    Erik's Analysis:

    With Nick Bosa back, the 49ers defense should hold the marginal Pittsburgh offense in check. Meanwhile, San Francisco's offense still has some questions. If either team finishes with 17 or fewer points, the Under should hit.

    Pick Made: Sep 07, 11:21 pm UTC
    Point SpreadSan Francisco -2.5 -110
    WIN
    Unit1.0
    +1162.5
    50-31-1 in Last 82 NFL Picks
    Erik's Analysis:

    Pittsburgh is an average football team. San Francisco is loaded. The 49ers now have Nick Bosa in the fold and they should roll.

    Pick Made: Sep 07, 11:17 pm UTC
    Point SpreadPittsburgh +2.5 -110
    LOSS
    Unit1.0
    +1855
    122-86-1 in Last 209 NFL Picks
    +1153
    55-39-1 in Last 95 NFL ATS Picks
    +90
    2-1 in Last 3 SF ATS Picks
    Larry's Analysis:

    The 49ers' offensive line is going to be weaker this year, at least starting out, and that will be an issue in Pittsburgh. The Steelers went 8-2 with T.J. Watt in the lineup last season; he's fully healthy. Brock Purdy only faced one elite front four (Dallas) last year and the 49ers scored 19 points. Pittsburgh's first-team offense scored touchdowns on all five of its preseason possessions. The Steelers won't be that efficient Sunday, but they should cover if not win outright.

    Pick Made: Sep 07, 6:35 pm UTC
    Over / UnderUNDER 41.5 -110
    WIN
    Unit1.0
    +1333
    96-75-3 in Last 174 NFL Picks
    +450
    15-11 in Last 26 NFL O/U Picks
    +813
    17-8-3 in Last 28 PIT O/U Picks
    R.J.'s Analysis:

    The 49ers get back Nick Bosa in some fashion after his extension Wednesday, but George Kittle is nursing a groin injury and was among the many 49ers players limited to begin the week. We'll see how Brock Purdy's elbow holds up to a full game of action, and if he can even settle in the pocket with a great Pittsburgh pass rush attacking a 49ers OL that lost Mike McGlinchey this offseason. With the hook available at multiple books, I like the Under here.

    Pick Made: Sep 07, 2:05 pm UTC
    Point SpreadSan Francisco -2 -110
    WIN
    Unit1.0
    +247.5
    9-6-1 in Last 16 NFL Picks
    +25
    3-2 in Last 5 NFL ATS Picks
    +450
    5-0 in Last 5 SF ATS Picks
    Mike's Analysis:

    Nick Bosa is worth nearly two full points to the spread in my simulations, which brings this line to -3.5 for me despite the road matchup against another solid defensive team. I have questions about the 49ers' offense, but the combination of the skill position players and the defensive strength should be enough to win a competitive, low-scoring game. I'm laying the -2 road chalk here.

    Pick Made: Sep 07, 1:59 am UTC
    PropBrandon Aiyuk OVER 46.5 Total Receiving Yards -118
    WIN
    Unit1.0
    +721.5
    44-30 in Last 74 NFL Player Props Picks
    Alex's Analysis:

    Brandon Aiyuk is coming off a career season where he eclipsed 1,000 yards for the first time, in addition to posting a very respectable 1.71 yards per route run, both of which led the team. Aiyuk averaged 59 receiving yards per game and logged close to a 100% route participation with Brock Purdy under center. George Kittle has yet to practice this week and if he is unable to suit up that could funnel additional targets to Aiyuk. Either way I feel this number is closer to Aiyuk's floor and the 4th year WR is poised for a big season.

    Pick Made: Sep 06, 5:59 pm UTC
    Point SpreadPittsburgh +2.5 -110
    LOSS
    Unit1.0
    +562.75
    69-55-1 in Last 125 NFL Picks
    +210
    10-7 in Last 17 SF ATS Picks
    Matt's Analysis:

    Wow, Nick Bosa signed today so he will presumably play, but what kind of football shape is he in after a 43-day holdout? SF also is breaking in a new DC. Star TE George Kittle is in question. QB Brock Purdy barely threw the ball this offseason recovering from injury. I try not to get too excited about the preseason -- see Cade McNown (McNo!!!) -- but Pittsburgh looked fantastic. The Steelers were 8-2 when T.J. Watt played last season and 1-6 when he did not. Watt is healthy now. I believe the Steelers win outright (yes, even with Bosa although my confidence level dropped a little) but I'll not turn down points and this is dropping so why not waiting.

    Pick Made: Sep 06, 5:30 pm UTC
    Point SpreadPittsburgh +2.5 -110
    LOSS
    Unit1.0
    +2098
    67-46-3 in Last 116 NFL ATS Picks
    +2250
    49-24-1 in Last 74 PIT ATS Picks
    R.J.'s Analysis:

    The 49ers are considered one of the best teams in football, but they suffered more losses in the offseason than I think most people realize. The offensive line could be an issue after Mike McGlinchey's departure, and we know the Steelers have an elite pass rush. The San Francisco defense lost its DC and plenty of depth, and while Nick Bosa is back, he likely won't see his usual workload just days after reporting. Then you have Brock Purdy, who looked fine in limited preseason work but now has to do it over four quarters. It all lines up for an underrated Steelers team to get a surprise win in Week 1.

    Pick Made: Sep 06, 2:49 pm UTC

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    Team Injuries

    San Francisco 49ers
    Monday, Dec 04, 2023
    Avatar
    DE
    Arik Armstead
    FootQuestionable
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    WR
    Ray-Ray McCloud
    RibsQuestionable
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    TE
    Ross Dwelley
    AnkleDoubtful
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    OG
    Spencer Burford
    KneeQuestionable
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    CB
    Darrell Luter Jr.
    HamstringDoubtful
    Pittsburgh Steelers
    Tuesday, Dec 05, 2023
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    RB
    Najee Harris
    KneeQuestionable
    Monday, Dec 04, 2023
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    C
    Mason Cole
    NeckQuestionable
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    CB
    James Pierre
    ShoulderQuestionable
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    QB
    Kenny Pickett
    AnkleOut
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    DT
    Keeanu Benton
    ObliqueQuestionable
    Sunday, Dec 03, 2023
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    OG
    Isaac Seumalo
    ShoulderQuestionable
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    OLB
    Elandon Roberts
    GroinQuestionable