Buffalo 31 @ New Orleans 6 | 11/26 | 1:20 AM UTC
ANALYSIS: Taking the worst line of the week here with the Bills, though it should come down to -6.5 again before kickoff. Though this is a marginal pick (I have Buffalo as an 8-point favorite), the absences of Alvin Kamara and Mark Ingram really deplete an already thin group of playmakers. The Saints defense, which has been praised endlessly this season, has allowed 29.3 points per game over the last four contests. If New Orleans is unable to sustain drives, Buffalo is going to have chance after chance to light up the scoreboard. The Bills are better their record and need a get-right spot. This should be it.