ANALYSIS: Buffalo is in desperate need of a "get-right" game, after what we saw Sunday against the Colts. The Bills get exactly that in a Saints team coming off a bad loss to the Eagles, one in which they gave up more than 200 yards rushing on the ground. Without Alvin Kamara and a questionable Mark Ingram, this Saints offense will be all on the shoulders of QB Trevor Siemian. That's not a good look for New Orleans.

ANALYSIS: Both teams got handed bad losses last weekend. However, with a new game brings new optimism. We know the Cowboys' offense is much better than what we saw Sunday against Kansas City, even without Amari Cooper. We also know Las Vegas' defense isn't the best at minimizing big plays. Look for the Dallas offense to get back on the right track at home.

ANALYSIS: Even at this juncture of his career, Andy Dalton is a much better quarterback than Jared Goff. That's not what you want to hear if you're a Lions fan, as Goff will be tied to this offense for at least one more season. This game will be close because of the quick turnaround nature. But with Goff returning from an oblique injury, who knows how effective he'll be against an aggressive Bears defense.

ANALYSIS: What a matchup this is between two electric offenses. I know folks may think that term doesn't describe the Chiefs' unit this year, but I still have hope that what we saw against Las Vegas wasn't an aberration, but more of a sign of things to come. What I also believe is that the Cowboys are a much better team on both sides of the ball than Kansas City and will be able to go into Arrowhead Stadium and get a win.

ANALYSIS: All signs point to Cam Newton starting at QB for Carolina, which makes things that much more intriguing. Without Washington DE Chase Young (knee) up front, it also makes things a bit easier for the Panthers' offensive line. Washington is coming off of a strong effort against Tampa Bay, but I don't particularly like the matchup here against a Panthers team that has a competent QB under center.