Joe Milton has thrown for 286 yards and three touchdowns in the Cowboys' two preseason wins, which both came by 10-plus points. Neither team will play their starters, so this comes down to who has the better backups and roster depth. That certainly appears to be Dallas. New Orleans is 0-2 and has been trucked 32-0 in the second half.

Undrafted free agent QB Joe Fagnano has one more chance to impress. In the first two preseason games, Fagnano completed 77.1 percent of his passes for 347 yards and two touchdowns with one interception. In this same matchup to end the 2025 preseason, the Ravens won 30-3. It likely won't be that lopsided this time, but I still like fading Dan Quinn in this spot.

The Cards have lost five straight and are calling up lefty Cooper Hjerpe to make his MLB debut. St. Louis averages just 3.78 runs at home. Trevor Rogers has allowed three or fewer runs in 13 of his last 14 starts, posting a 2.57 ERA in that span. Back the O’s to get the sweep.

Michael McGreevy is a major regression candidate, with an expected ERA of 5.31 and an expected slugging percentage of .481. The Orioles should have a starting pitching edge with Kyle Bradish going, plus their bullpen is in good shape. Look for St. Louis to drop its fifth straight.

Peter Lambert was shellacked last time out at home, but on the road the Astros' starter owns a 2.98 ERA with just over one strikeout per inning. He's facing a Yankees lineup that has fanned at the second-highest rate over the past month. Lambert has struck six-plus batters in six of his last nine outings. I would also play this Over 5.5 strikeouts at plus money.

Sean Payton said Bo Nix will play about 14 snaps in his return Friday from a fractured right ankle. While the Packers also will play their starters some, Denver has been a preseason machine, winning eight straight. The Broncos have scored 27 or more points in seven of those eight. Playing at altitude won't be easy for the Packers, who got blown out at Pittsburgh last week.

Malik Willis has taken a step forward in practices lately and will play, along with some other starters. The Commanders also will play some starters but there are bigger injury concerns on Washington’s side. Dan Quinn went 0-3 straight-up in the preseason last year and is 7-20 alltime. Miami may not get more than a few regular-season wins but I like the Dolphins here at less than a field goal.

Titans coach Robert Saleh's first preseason game comes at San Francisco, where he served as defensive coordinator last season and also from 2017-20. While both teams will put more emphasis on Tuesday's joint practice, I'm betting Tennessee will care more about Thursday's game. The 49ers scheduled practices for Saturday and Sunday -- important opportunities for relevant players -- while the Titans won't practice again until Monday. Saleh is 10-2-1 straight-up in the preseason, 10-3 ATS. The Titans' main backup quarterbacks, Mitchell Trubisky and Will Levis, both have plenty of NFL starting experience. Tennessee is the only road team favored Thursday for a reason.

The Brewers have won Logan Henderson's last eight starts. He carries a 0.90 WHIP into Monday's matchup at San Diego. The Padres are hot, but starter Casey Mize might not be benefitting from a change of scenery. The former Tiger got lit up in his first start with the Padres, giving up eight earned runs in 3.1 innings to Arizona.

Robbie Ray aims to make a good first impression with the Padres, hoping to continue a stretch in which he's 7-0 in his last 12 appearances. He posted a 2.00 ERA in July and a 1.36 ERA in June. The Astros rank 17th in OPS against lefties. The Padres' offense has picked up lately. While it's not on Houston's level, the pitching edge makes this price attractive.

The Panthers are coming off a division title, and they've already suffered several significant injuries in training camp. Expect Dave Canales, who is 0-6 ATS in preseason games, to prioritize health. Kenny Pickett will start for the Panthers, then undrafted free-agent Haynes King will make some plays with his arm and legs. But the Cardinals have the edge with Carson Beck starting. The third-round pick, who led Miami to the 2026 College Football Playoff National Championship Game, struggled early in camp but turned a corner recently. His backup, Kedon Slovis, has extensive preseason experience. New coach Mike LaFleur has set an intense tone in camp. This game means more to the upstart Cardinals.

Mariners starter Bryce Miller is 3-0 with a 0.00 ERA in four career appearances against Detroit. That includes a June 6 start in which he fanned nine and allowed one hit over six innings. Tigers starter Framber Valdez is 2-4 with a 4.68 ERA on the road, walking 25 batters in 65.1 innings. Back the Mariners in the rubber game.

This will be Hayden Wesneski's second start since returning from Tommy John surgery. He did OK in his 2026 debut, allowing three earned runs in 5.2 innings vs. the Angels. However, he gave up seven hits and two walks. Blue Jays starter Trey Yesavage has a good chance to hold down Houston's righty-heavy lineup; his K rate goes up and his walk rate goes down against righties, who are batting .180 against him. On June 24, Yesavage held the Astros to one run on two hits over 5.2 innings. Look for Toronto to at least be tied through five.

Michael Lorenzen, 34, remains one of MLB's worst pitchers. At Coors Field, he's 1-4 with an 8.34 ERA in 10 starts. He ranks near the bottom in a slew of advanced metrics. On Monday he faces a frustrated Rays lineup that has scored 14 runs in its last eight games, including just three in a weekend series against the White Sox. Current Rays' batters own a 1.079 OPS against Lorenzen. Whether Ian Seymour (2 runs allowed in his last 10.2 innings, 0.91 WHIP over his last seven outings) starts or follows an opener, I like the Rays to lead after five.

The Brewers are 36-20 at home, and I like their chances of jumping on Bubba Chandler and the Pirates’ pen. He sports a 1.41 WHIP and struggles with command. On July 11 vs. the Brewers, Chandler walked three and needed 97 pitches to complete 4.2 innings. Several Milwaukee batters have a good, albeit brief history against Chandler. I would not play this higher than -145.