loading...
League Logo
NFL
League Logo
NFL
League Logo
CFB
League Logo
NBA
League Logo
CBB
League Logo
NHL
All
  • Loading...
loading...
Sun, Sep 225:00 pm UTCLucas Oil Stadium
Chicago
Bears
CHI
Last 5 ATS
W/L5-12
ATS9-7
O/U7-10-0
FINAL SCORE
16
-
21
Indianapolis
Colts
IND
Last 5 ATS
W/L8-9
ATS9-8
O/U9-7-1
SPREAD
MONEYLINE
OVER/UNDER
Last 5 ATS
5-12
Win /Loss
8-9
9-7
Spread
9-8
7-10-0
Over / Under
9-7-1
SPREAD
MONEYLINE
OVER/UNDER

Simulation Picks

SPREAD
CHI @ IND
Subscribers Only

Maximize Your Odds of Winning with SportsLine Model and Our Top-Rated Picks

MONEYLINE
CHI @ IND
Subscribers Only

Maximize Your Odds of Winning with SportsLine Model and Our Top-Rated Picks

OVER / UNDER
CHI @ IND
Subscribers Only

Maximize Your Odds of Winning with SportsLine Model and Our Top-Rated Picks

55%
PUBLIC
45%
MONEY
37%
PUBLIC
63%
MONEY
Over54%
PUBLIC
Under46%
Over
MONEY
Under

Understanding Public and Money

Think of 'Public' as the percentage of people betting on each side and 'Money' as how much money is being bet. When there's a big difference between the 'Public' and 'Money' data, it usually means that the more serious bettors (referred to as 'Sharp Money') are favoring a particular side.

Expert Picks

Point SpreadIndianapolis -1.5 -110
WIN
Unit1.0
+2577
84-53-4 in Last 141 NFL ATS Picks
+31
7-6-1 in Last 14 CHI ATS Picks
Adam's Analysis:

The Colts have a few edges in this game, most notably on the sidelines. The Bears should have more offensive opportunities against a tough-to-stomach Indianapolis run defense, but they have not proven they can run the ball successfully, and Caleb Williams still needs to actually make his throws. We have seen him struggle with that through two games as he continues to get adjusted to the NFL. Anthony Richardson has simultaneously been flashy and disappointing, as expected, but his big arm and physical style should allow enough chunk plays. This is a legitimate must-win for Indy already in Week 3, which should be motivated to overcome last week’s embarrassment.

Pick Made: Sep 22, 4:21 pm UTC on Caesars
Money LineIndianapolis -118
WIN
Unit1.0
+331
10-6 in Last 16 NFL Picks
+112
9-6 in Last 15 NFL ML Picks
+263
4-1 in Last 5 IND ML Picks
Josh's Analysis:

The Colts are just a couple plays away from being 2-0, instead they are 0-2 and in desperation mode to avoid an 0-3 start that would essentially spell the death knell on their playoff hopes. The Bears don't have a strong enough run game to exploit the weakness of the Indy defense, and we'll back what should be an inspired Colts team to escape with a win.

Pick Made: Sep 22, 3:13 pm UTC on BetRivers
Avatar
Total CarriesD'Andre Swift Over 13.5 Total Carries -102
LOSS
Unit1.0
Thomas's Analysis:

I have to think the Bears try to get Swift going versus the NFL's 32nd ranked rush defense to take pressure off Caleb Williams. Even though Swift was bottled up last week against the Texans, he still carried the ball 14 times. Josh Jacobs carried the ball 32 times versus the Colts and now Indy is without DeForest Buckner. Swift should be in line for a heavy workload on Sunday.

Pick Made: Sep 22, 5:51 am UTC on FanDuel
Point SpreadIndianapolis -1 -110
WIN
Unit1.0
+2007
61-37-3 in Last 101 NFL ATS Picks
Mike's Analysis:

The primary risk with starting rookie QBs from the get-go is they can become shell-shocked. Houston sacked Caleb Williams seven times last Sunday, and he has yet to throw a TD pass. Rookies need a full complement of help, and Williams won't have it with WR Keenan Allen out. Williams will be a star someday but not likely soon. A beat-up Colts defense should be able to contain Chicago enough for big-play QB Anthony Richardson, who tops the league for passing yards per attempt, to bedevil a defense that gets victimized by large gains.

Pick Made: Sep 21, 7:27 pm UTC on Caesars
Avatar
Total Receiving YardsDJ Moore Over 63.5 Total Receiving Yards -114
WIN
Unit1.0
Eric's Analysis:

If Moore doesn't blow up this week against the likes of Jaylon Jones, Dallis Flowers, and Samuel Womack III, I have no idea what to tell you about his 2024 outlook. This should be a get right spot for a player with a 27% target share and 36% air yards share through two weeks. I'm thinking 75+ yards seems well within reach against this inexperienced Colts secondary, assuming Caleb Williams' accuracy improves for Chicago.

Pick Made: Sep 20, 12:43 am UTC on FanDuel
Point SpreadIndianapolis -1.5 -105
WIN
Unit1.0
+1879
45-24-1 in Last 70 NFL Picks
+1814
39-19-1 in Last 59 NFL ATS Picks
Emory's Analysis:

The Colts have the offensive talent to be explosive, but they have to get off to a fast start. Defensively, they should find some opportunities to get after rookie Caleb Williams. While I expect the Bears to play much better offensively against a sketchy Colts defense, Indy finds themselves in a 'must win' situation here in Week 3 and subsequently we'll see them play their best ball.

Pick Made: Sep 18, 1:39 pm UTC on FanDuel
Point SpreadChicago +2 -110
LOSS
Unit1.0
+1475
55-37 in Last 92 NFL Picks
+775
53-41-1 in Last 95 NFL ATS Picks
+1018
28-16-3 in Last 47 IND ATS Picks
R.J.'s Analysis:

The Bears offense has been awful through two weeks, gaining half a yard per play less than the Panthers. But the defense has picked up where it left off last season, carrying the team to a win in Week 1 then holding an explosive Texans attack to just one TD in Houston. That D gets a Colts attack that boomed in Week 1 and busted in Week 2, and I expect they'll struggle against a strong Chicago stop unit. The Bears offense should finally have some success against a Colts defense that's been run all over even against an offense without a threat to pass last week. I don't see DeForest Buckner returning for this game, making Indy's defensive issues even greater.

Pick Made: Sep 17, 2:43 pm UTC on DraftKings

Team Injuries

Chicago Bears
Friday, Dec 12, 2025
Avatar
RB
Travis Homer
AnkleOut
Monday, Dec 08, 2025
Avatar
WR
Rome Odunze
FootQuestionable
Indianapolis Colts
Friday, Dec 12, 2025
Avatar
CB
Sauce Gardner
CalfOut
Avatar
WR
Anthony Gould
FootOut
© 2025 CBS INTERACTIVE INC. ALL RIGHTS RESERVED. SportsLine and SportsLine PRO are registered trademarks of SportsLine.com, Inc.FANS ONLY
In partnership with...247 Sports

FOLLOW US:

The content on this site is for entertainment purposes only and SportsLine makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event. There is no gambling offered on this site. This site contains commercial content and SportsLine may be compensated for the links provided on this site.