The 49ers should likely be a double-digit favorite in this spot, but clearly there is some hesitancy to trust Brock Purdy against a strong Commanders defense. Even with Purdy under center, San Francisco’s offense is light years ahead of the one Washington brings to the table. The 49ers are 6-1 ATS since Christian McCaffrey became a full-fledged member of the offense (7-0 straight up), and they’ve won their last three home games by an average of 19 points, two of those being double-digit victories against potential playoff teams. There’s a chance this hits -6 before kickoff, so see if that comes or you can buy -6 (-115). If not, I’m still comfortable with the hook.

As great as the 49ers' streak has been, their spread value is now teetering, based on their seven-game win streak. With extra days off following their Thursday victory over Seattle, I believe we will see some rust from San Francisco. Washington has a very solid defense, and of course Ron Rivera is familiar with the strengths of running back Christian McCaffrey. Take the big points here with Washington.

The 49ers have won seven straight (6-1 ATS) and it looks like rookie QB Brock Purdy is quite comfortable with an offense that is loaded with weapons. There should be no weather issues in Santa Clara like most of the country is seeing. The 49ers are 6-1 at home. Washington had won six of seven (7-0 ATS) until tying the Giants, then losing to them last week. Coach Ron Rivera indicated Carson Wentz might be needed soon, hoping to give a spark to erratic starter Taylor Heinicke. But I’m betting it will have the opposite effect. Back the 49ers to cover at home.

The 49ers have allowed 11 points per game during their seven-game win streak, with no opponent scoring more than 17. Taylor Heinicke lost two crucial fumbles on sacks in Washington's 20-12 home loss to the Giants, and now he'll face a ferocious defense that's hit a new level since Arik Armstead returned to the lineup in Week 13. Washington will lean on the run, but the 49ers allow a league-low 3.4 yards per carry. San Francisco has a rest edge heading into this game, and Brock Purdy has done nothing but impress. In the last three games, he's thrown six touchdowns and one interception while completing 69% of his throws. Lay the touchdown.