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Thu, Nov 245:30 pm UTCFord Field
Buffalo
Bills
BUF
Last 5 ATS
W/L13-3
ATS8-8
O/U6-10-0
FINAL SCORE
--
-
--
Detroit
Lions
DET
Last 5 ATS
W/L9-8
ATS12-5
O/U10-7-0
SPREAD
MONEYLINE
OVER/UNDER
Last 5 ATS
13-3
Win /Loss
9-8
8-8
Spread
12-5
6-10-0
Over / Under
10-7-0
SPREAD
MONEYLINE
OVER/UNDER

Simulation Picks

SPREAD
BUF @ DET
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MONEYLINE
BUF @ DET
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OVER / UNDER
BUF @ DET
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0%
PUBLIC
0%
MONEY
0%
PUBLIC
0%
MONEY
Over0%
PUBLIC
Under0%
Over
MONEY
Under

Understanding Public and Money

Think of 'Public' as the percentage of people betting on each side and 'Money' as how much money is being bet. When there's a big difference between the 'Public' and 'Money' data, it usually means that the more serious bettors (referred to as 'Sharp Money') are favoring a particular side.

Expert Picks

Buffalo -9.5 -110
LOSS
Unit1.0
+2577
84-53-4 in Last 141 NFL ATS Picks
+1696
48-28-2 in Last 78 NFL ATS Picks
Adam's Analysis:

While not overly fond of double-digit road favorites, the Bills set up nicely in this spot given their recent familiarity with Ford Field and the return to health of starting cornerbacks Kaiir Elam and Tre'Davious White. Elam no longer carries an injury designation, and White is active for the first time after a torn ACL one year ago. That should help slow down a solid Lions offense, which has feasted on short fields by taking advantage of turnovers the last three weeks (+7). Josh Allen has thrown as many bad picks as any quarterback in the league, but he seemed to figure things out last week. Buffalo's wideouts should have a field day on this Detroit defense. I'd prefer to live bet and see if we can get below a touchdown as the Bills generally start slow, but I gotta have action on Thanksgiving, so we'll do a half unit here on the better team with more at stake getting key defensive reinforcements back even if this is a game from which I'd normally stay away.

Pick Made: Nov 24, 4:27 pm UTC on WHNJ
Detroit +9.5 -110
WIN
Unit1.0
+1938
37-12 in Last 49 NFL ML Picks
+1076
22-10 in Last 32 NFL ATS Picks
Matt's Analysis:

As a former Michigander, I have been to a couple of Lions games on Thanksgiving. Usually the best crowd of the year. My point being is while sometimes home-field advantage is overrated, I think it matters today. Detroit is playing easily the best it has under Dan Campbell led by unlikely NFL rushing TD leader Jamaal Williams. I frankly wouldn't be shocked if the Lions win this game outright. Not predicting that but will take the points.

Pick Made: Nov 24, 3:41 pm UTC on WHNJ
Detroit +9.5 -110
WIN
Unit1.0
+1879
45-24-1 in Last 70 NFL Picks
+90
2-1 in Last 3 NFL ATS Picks
Emory's Analysis:

Both teams do a really good job of putting the ball in the paint. The Lions are on a three game winning streak, and seems to have found its rhythm on offense, playing with much more balance. We know that Buffalo can score the ball and are getting healthier by the week on defense. I expect a back and forth affair, especially when you combine the fact that the Lions are playing some of their best ball of the season, makes this point spread a bit too much for me.

Pick Made: Nov 24, 1:11 pm UTC on WHNJ
Detroit +9.5 -110
WIN
Unit1.0
+2425
44-18-4 in Last 66 NFL ATS Picks
+655
11-4 in Last 15 NFL ATS Picks
Mike's Analysis:

Detroit has dropped five consecutive Turkey Day games outright, but the Lions' season is too often in ruins by this week. Not so now, with Detroit riding a three-game straight-up streak that will ignite the crowd. Props to the Bills for beating Cleveland in this same stadium, but the back-and-forth travel and short week could take its toll. Nor will Buffalo have nearly as many supporters as it drew against the Browns. The Lions have put up 25.67 ppg during the run while allowing 19. The impressive differential places them in position to take this matchup down to the wire.

Pick Made: Nov 22, 5:38 pm UTC on WHNJ
Detroit +9 -110
WIN
Unit1.0
+2053
98-78-4 in Last 180 NFL Picks
+681
29-20-1 in Last 50 NFL ATS Picks
R.J.'s Analysis:

The Lions are on a three-game winning streak despite getting severely outgained in yardage in each game thanks to securing key turnovers, even against teams like the Giants that know how to protect the ball. The Bills surprisingly have the most turnovers per game in the league, though they finally had a clean game against Cleveland. The Bills are in a brutal travel spot going back and forth to Detroit for this early Thursday start, and they could be sluggish out the gate. The Lions are strong enough in the trenches to keep this one from getting out of hand, especially if they can continue to generate turnovers against a turnover-prone offense.

Pick Made: Nov 21, 6:28 pm UTC on WHNJ

Team Injuries

Buffalo Bills
Wednesday, Dec 17, 2025
Avatar
OT
Dion Dawkins
IllnessQuestionable
Avatar
TE
Dalton Kincaid
KneeQuestionable
Monday, Dec 15, 2025
Avatar
K
Matt Prater
QuadricepsOut
Avatar
WR
Brandin Cooks
UndisclosedQuestionable
Avatar
DT
Jordan Phillips
AnkleOut
Avatar
LB
Terrel Bernard
ElbowQuestionable
Avatar
CB
Christian Benford
ToeQuestionable
Detroit Lions
Wednesday, Dec 17, 2025
Avatar
OT
Taylor Decker
ShoulderQuestionable
Avatar
C
Trystan Colon-Castillo
WristQuestionable
Avatar
RB
Sione Vaki
ThumbQuestionable
Monday, Dec 15, 2025
Avatar
CB
Amik Robertson
HandQuestionable
Avatar
SAF
Kerby Joseph
KneeQuestionable
Avatar
SAF
Thomas Harper
ConcussionQuestionable
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