ANALYSIS: The Bills are 4-0-1 ATS in their last five home games, and they’ll be facing a rookie QB making his first NFL start on the road. It’s Kenny Pickett time for the Steelers, who have started the season 1-3 behind the 30th ranked offense and a defense without T.J. Watt. The Bills have a slew of injuries, notably the entire secondary, wide receiver and tight end Dawson Knox. But the biggest reason for siding with Pittsburgh is the point spread. This is a lot of points for an NFL game. I took the points with the Steelers.