San Francisco 33 @ Chicago 22 | 10/31 | 5:00 PM UTC
San Francisco -3
ANALYSIS: Every book I can find has the Niners at -3.5 but for Caesars, so let's take the value now because Chicago will be without Pro Bowl pass-rusher Khalil Mack due to injury. Stud defensive tackle Akiem Hicks missed Week 7 and is in major question, too. Pass-rusher Robert Quinn also is iffy on the COVID list. Embattled coach Matt Nagy is on the COVID list as well but that may only help Chicago.