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In his last eight regular-season games, Brock Purdy cleared this prop total twice, each time by a half-yard. He's facing a fierce Rams' pass rush led by Myles Garrett (23 sacks), Byron Young (12 sacks) and Kobie Turner (7 sacks). The Rams also upgraded their secondary with the additions of corners Trent McDuffie and Jaylen Watson. I'm expecting a lot of short, quick throws from Purdy and bet against him completing one of 38-plus yards.

Deebo Samuel is back in a comfortable offensive system, and the 49ers need him. George Kittle returns from a serious injury and could be limited. Mike Evans dealt with multiple injury issues during training camp, and the other primary target (outside of Christian McCaffrey) is rookie De'Zhaun Stribling. Look for Samuel to be heavily involved vs. the Rams.

DeMario Douglas caught five of seven targets for 45 yards in the Super Bowl loss to the Seahawks. Stefon Diggs is gone, so Douglas should be the primary slot receiver. That's an important role against a Seahawks defense that could be missing Nick Emmanwori (ankle). With Seattle focused on slowing down A.J. Brown and Romeo Doubs on the outside, look for Douglas to notch at least 20 receiving yards.

Seahawks first-round pick Jadarian Price didn't play a preseason snap, but that was to preserve him for games like this. He'll make his NFL debut against a Patriots' run defense that lost nose tackle Khyiris Tonga to the Chiefs and proved vulnerable to zone rushing schemes last season. Seattle returns its entire offensive line. While George Holani is expected to mix in on passing downs, Price showed excellent receiving skills in the Seahawks' joint practice with the Titans, catching multiple passes. Sam Darnold called him "a special palyer." Price averaged 10.8 yards per reception at Notre Dame, though he wasn't targeted much, along with 6.0 yards per carry. Look for Price to be heavily involved Wednesday.

Kade Anderson fanned a whopping 135 batters in 93.1 innings in Class AA before getting promoted to the Mariners. In his third major-league start, he'll face an Athletics lineup that strikes out vs. southpaws at the seventh-highest rate. Pitching at home, look for Anderson to go at least five innings and rack up at least six strikeouts.

I'm fading Spencer Arrighetti, who is expected to have the bulk role after opener Spencer Miles. Since returning from a condition that causes nerve pain in his foot, the 26-year-old Arrighetti has been ineffective. He's made two starts for Toronto, giving up six earned runs in 7.1 innings on eight hits and four walks. Guardians starter Gavin Williams is 6-3 with a 3.27 ERA at home and should bounce back strong from his worst outing of the season.

Joe Milton has thrown for 286 yards and three touchdowns in the Cowboys' two preseason wins, which both came by 10-plus points. Neither team will play their starters, so this comes down to who has the better backups and roster depth. That certainly appears to be Dallas. New Orleans is 0-2 and has been trucked 32-0 in the second half.

Undrafted free agent QB Joe Fagnano has one more chance to impress. In the first two preseason games, Fagnano completed 77.1 percent of his passes for 347 yards and two touchdowns with one interception. In this same matchup to end the 2025 preseason, the Ravens won 30-3. It likely won't be that lopsided this time, but I still like fading Dan Quinn in this spot.

The Cards have lost five straight and are calling up lefty Cooper Hjerpe to make his MLB debut. St. Louis averages just 3.78 runs at home. Trevor Rogers has allowed three or fewer runs in 13 of his last 14 starts, posting a 2.57 ERA in that span. Back the O’s to get the sweep.

Michael McGreevy is a major regression candidate, with an expected ERA of 5.31 and an expected slugging percentage of .481. The Orioles should have a starting pitching edge with Kyle Bradish going, plus their bullpen is in good shape. Look for St. Louis to drop its fifth straight.