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Sat, Sep 3011:30 pm UTCBrooks Field at Wallace Wade Stadium
69 F
Notre Dame
Fighting Irish
ND
Last 5 ATS
W/L8-3
ATS8-3
O/U8-4-0
FINAL SCORE
21
-
14
Duke
Blue Devils
DUKE
Last 5 ATS
W/L6-5
ATS6-6
O/U7-4-1
SPREAD
MONEYLINE
OVER/UNDER
Last 5 ATS
8-3
Win /Loss
6-5
8-3
Spread
6-6
8-4-0
Over / Under
7-4-1
SPREAD
MONEYLINE
OVER/UNDER

Simulation Picks

SPREAD
ND @ DUKE
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MONEYLINE
ND @ DUKE
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OVER / UNDER
ND @ DUKE
Subscribers Only

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57%
PUBLIC
43%
MONEY
50%
PUBLIC
50%
MONEY
Over50%
PUBLIC
Under50%
Over
MONEY
Under

Understanding Public and Money

Think of 'Public' as the percentage of people betting on each side and 'Money' as how much money is being bet. When there's a big difference between the 'Public' and 'Money' data, it usually means that the more serious bettors (referred to as 'Sharp Money') are favoring a particular side.

Expert Picks

Point SpreadNotre Dame -5.5 -110
WIN
Unit1.0
+541
12-6 in Last 18 ND ATS Picks
Adam's Analysis:

In no scenario should Duke be discounted. Mike Elko has done an incredible job with his veteran-laden roster, and Riley Leonard has done an incredible job himself moving this Blue Devils offense. The best reason to pick Duke is the emotional element with Notre Dame losing a hard-fought home game and now going on the road to a hostile environment. But I'm a huge fan of what Sam Hartman has done turning this Fighting Irish offense around. He's not only effective but efficient and protective of the ball. This should be a 7-point line, which gives us some value on Notre Dame. The Irish need to win every remaining game in impressive fashion if they hope to have any chance at the playoff.

Pick Made: Sep 30, 11:17 pm UTC on Consensus
Point SpreadNotre Dame -5.5 -110
WIN
Unit1.0
+190
3-1 in Last 4 NCAAF ATS Picks
+90
2-1 in Last 3 ND ATS Picks
Zack's Analysis:

The Irish let a golden opportunity falter at home last week against Ohio State. Led by quarterback Sam Hartman expect the Irish to regroup against a Duke team he is very familiar with. His last ACC game was a loss last year at Duke. He will have the Irish motivated and ready to play as they knock of the Blue Devils.

Pick Made: Sep 30, 9:40 pm UTC on WilliamHillNewJersey
Point SpreadNotre Dame -5.5 -110
WIN
Unit1.0
+356
8-4 in Last 12 ND ATS Picks
Mike's Analysis:

Had Notre Dame stopped Ohio State at the goal line and celebrated a win, this would be a stay-away game. Instead, the Irish will have shed their disappointment by kickoff against Duke and will likely extend their amazing straight-up win streak over ACC members to 30. Duke is legit, with able QB Riley Leonard and a fly-to-the-ball defense. But it must deal with big-boy football. The Damers own a significant size advantage. They can spotlight RB Audric Estime, the nation's top rusher, which will open up passing lanes for QB Sam Hartman. The setting in rowdy Durham will be challenging, but it's not like the Irish never invade hostile territory. Old hat for them.

Pick Made: Sep 30, 3:34 pm UTC on Bet365NewJersey
Over / UnderUnder 53 -110
WIN
Unit1.0
+1628.5
74-53-1 in Last 128 NCAAF Picks
+649.5
16-10 in Last 26 NCAAF O/U Picks
Matt's Analysis:

Very curious how the Irish respond to the gut-punch last-second loss to Ohio State (thus, I have no opinion on the side), but if Notre Dame's stellar defense held that Nuts offense full of future NFL players to 17 points what might it do at Duke? The Blue Devils are a very good defensive team as well under Coach Mike Elko -- the former DC in South Bend. Notre Dame likely will be without top WR Jayden Thomas (13/195/1). This should be a very run-heavy game.

Pick Made: Sep 28, 8:41 pm UTC on Bet365NewJersey
Point SpreadDuke +6 -110
LOSS
Unit1.0
+290
4-1 in Last 5 ND ATS Picks
Bruce's Analysis:

Well, if schedule dynamics mean anything, edge Blue Devils, who rarely worked up a sweat last week in rolling past UConn while the Domers were battling down to the last second, literally, vs. Ohio State. Mike Elko is also familiar with ND QB Sam Hartman, who was outpassed by Riley Leonard last November (391-347 yards) in Duke's 34-31 win. Elko also isn't defending Dave Clawson's slow-mesh this time, and there will be pressure the other way on Marcus Freeman's defense to slow down the best dual-threat QB (Leonard) it might see all season. The Irish's unlikely 29-game reg.-season win streak vs. the ACC has caught all sorts of breaks along the way and will be hard-pressed to get to 30.

Pick Made: Sep 27, 6:17 pm UTC on WilliamHillNewJersey
Point SpreadNotre Dame -5.5 -110
WIN
Unit1.0
+418
34-27-1 in Last 62 NCAAF ATS Picks
+250
8-5 in Last 13 ND ATS Picks
Micah's Analysis:

Duke is definitely a football school now with QB Riley Leonard wreaking havoc on all four defenses he’s played this season. Duke returned 17 starters and it’s all coming together at 4-0. They beat Clemson in the opener. Notre Dame brought back 15 starters including four offensive linemen and brought in QB Sam Hartman to run the show. Hartman has 14 TDs and no picks through five games and comes off the 3-point loss to Ohio State. Notre Dame’s defense will be the toughest Leonard has seen this season and the Duke defense will struggle just enough with Hartman. I’m on Notre Dame to cover.

Pick Made: Sep 26, 6:56 pm UTC on WilliamHillNewJersey
Over / UnderUnder 52.5 -110
WIN
Unit1.0
+916
65-51-3 in Last 119 NCAAF Picks
Emory's Analysis:

This game is a monumental one for the Duke Blue Devils, who have already proven they can handle the bright lights. In Week 1 they held Clemson to 7 points in an upset win, and have only allowed one opponent to score in double-digits. ND plays the same game as Duke does, so look for this one to be a defensive slugfest down in Durham.

Pick Made: Sep 26, 3:08 pm UTC on WilliamHillNewJersey

Team Injuries

Notre Dame Fighting Irish
Sunday, Nov 30, 2025
Avatar
TE
Cooper Flanagan
Achilles
Monday, Nov 24, 2025
Avatar
LB
Kyngstonn Viliamu-Asa
Knee
Saturday, Nov 22, 2025
Avatar
K
Noah Burnette
Hip
Monday, Nov 17, 2025
Avatar
WR
Jaden Greathouse
Hamstring
Wednesday, Oct 15, 2025
Avatar
OL
Ashton Craig
Knee
Wednesday, Oct 01, 2025
Avatar
RB
Dylan Devezin
Shoulder
Avatar
RB
Kedren Young
Knee
Duke Blue Devils
Monday, Dec 08, 2025
Avatar
S
Terry Moore
Undisclosed
Avatar
RB
Peyton Jones
Transfer Portal
Avatar
CB
Kimari Robinson
Undisclosed
Wednesday, Oct 01, 2025
Avatar
LB
Nick Morris Jr.
Undisclosed
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