Samuel caught five of six targets for 26 yards and a touchdown while also adding 44 yards on three carries and 49 kickoff-return yards during Sunday's 24-14 win over the Broncos.
McCaffrey rushed 15 times for 52 yards and a touchdown and brought in three of five targets for 18 yards in the 49ers' 24-14 win over the Broncos on Sunday.
Purdy completed 19 of 30 passes for 218 yards with two touchdowns and no interceptions while adding 10 carries for 29 yards in the 49ers' 24-14 win over the Broncos on Sunday.
Evans brought in five of eight targets for 76 yards in the 49ers' 24-14 win over the Broncos on Sunday.
Sigle suffered an ankle injury during Sunday's 24-14 win over the Broncos.
Stout (shoulder) returned to Sunday's game against the Broncos, Nick Wagoner of ESPN.com reports.
Stout (shoulder) is questionable to return to Sunday's game against the Broncos, Nick Wagoner of ESPN.com reports.
Juszczyk (knee) has been ruled out for the remainder of Sunday's game against the Broncos, Eric Branch of the San Francisco Chronicle reports.
Juszczyk exited Sunday's contest against the Broncos in the fourth quarter with a leg injury, Nick Wagoner of ESPN.com reports.
Shrader went 3-for-3 on field-goal attempts and made all three of his PATs in Sunday's 30-13 win over Washington.
