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Sun, Sep 285:00 pm UTCHighmark Stadium
69 F
New Orleans
Saints
NO
Last 5 ATS
W/L4-9
ATS6-8
O/U4-10-0
FINAL SCORE
19
-
31
Buffalo
Bills
BUF
Last 5 ATS
W/L9-4
ATS7-7
O/U7-7-0
SPREAD
MONEYLINE
OVER/UNDER
Last 5 ATS
4-9
Win /Loss
9-4
6-8
Spread
7-7
4-10-0
Over / Under
7-7-0
SPREAD
MONEYLINE
OVER/UNDER

Simulation Picks

SPREAD
NO @ BUF
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MONEYLINE
NO @ BUF
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OVER / UNDER
NO @ BUF
Subscribers Only

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30%
PUBLIC
70%
MONEY
3%
PUBLIC
97%
MONEY
Over31%
PUBLIC
Under69%
Over
MONEY
Under

Understanding Public and Money

Think of 'Public' as the percentage of people betting on each side and 'Money' as how much money is being bet. When there's a big difference between the 'Public' and 'Money' data, it usually means that the more serious bettors (referred to as 'Sharp Money') are favoring a particular side.

Expert Picks

Avatar
InterceptionsJosh Allen Under 0.5 Total Passing Interceptions -177
LOSS
Unit0.5
+104
24-16 in Last 40 NFL Player Props Picks
Matt's Analysis:

Buffalo has gone eight straight games as a team without a turnover, including playoffs, which is tied with the 2024 Chiefs for the longest streak with zero turnovers since 1933. Josh Allen's last pick was Week 16 last year vs. New England and that's his only INT in his past 12. Presumably the Bills get up big and get Allen out of there by the start of the fourth quarter.

Pick Made: Sep 26, 2:17 pm UTC on DraftKings
SpreadNew Orleans +16.5 -120
WIN
Unit1.0
+324
11-7-1 in Last 19 NFL Picks
+78
3-2 in Last 5 NFL ATS Picks
+692
19-11-1 in Last 31 BUF ATS Picks
Mike's Analysis:

In sum: too many points to spot any team (unless torn asunder by injury) this early in the season. The Saints were no pushovers in their first two outings, with losses by seven and five points. While Buffalo's offense can play Name That Score, the Bills' points allowance through three games ranks 20th, which offers hope to beleagured QB Spencer Rattler and crew. Two key defenders, LB Matt Milano and DT Ed Oliver, have not practiced this week. Most other sportsbooks have dropped the spread to 15.5, so the extra vig might be worth it to Saints backers to secure the extra point.

Pick Made: Sep 24, 8:47 pm UTC on BetMGM
1st Q Spread1st Quarter Buffalo -3.5 -112
WIN
Unit1.0
+57
3-2 in Last 5 NFL Game Props Picks
R.J.'s Analysis:

The Bills are coming into this game on extra rest after playing on Thursday in Week 3, and I expect the offense to come out firing. Buffalo has scored at least seven in all three first quarters this year, while its opponent has reached seven once. The Saints have yet to score in the first quarter while giving up more than three points twice. I'm hesitant to play the full game spread as New Orleans could cover through the backdoor if Allen is pulled at some point, but we don't have to worry about that with this first-quarter play.

Pick Made: Sep 24, 6:03 pm UTC on FanDuel

Team Injuries

New Orleans Saints
Sunday, Dec 21, 2025
Avatar
RB
Alvin Kamara
Knee - MCLInactive
Avatar
CB
Ugo Amadi
Coach's DecisionInactive
Avatar
TE
Foster Moreau
AnkleQuestionable
Avatar
OG
Cesar Ruiz
AnkleInactive
Avatar
DT
Khristian Boyd
Coach's DecisionInactive
Avatar
OT
Asim Richards
AnkleInactive
Avatar
DT
Bryan Bresee
KneeQuestionable
Avatar
CB
Rejzohn Wright
Coach's DecisionInactive
Avatar
TE
Zaire Mitchell-Paden
KneeInactive
Buffalo Bills
Sunday, Dec 21, 2025
Avatar
K
Matt Prater
QuadricepsInactive
Avatar
DT
Jordan Phillips
AnkleInactive
Avatar
OLB
Shaq Green-Thompson
NeckQuestionable
Avatar
DT
Larry Ogunjobi
Coach's DecisionInactive
Avatar
SAF
Darnell Savage
Coach's DecisionInactive
Avatar
WR
Gabe Davis
Coach's DecisionInactive
Avatar
OT
Tylan Grable
Coach's DecisionInactive
Avatar
WR
Keon Coleman
Coach's DecisionInactive
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