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Pickens tallied two catches (on four targets) for 48 yards during Sunday's 33-30 overtime loss to the Cardinals.
Prescott was 19-for-29 passing for 195 yards, one touchdown and no interceptions while rushing seven times for 20 yards and one more TD during Sunday's 33-30 overtime defeat to the Cardinals.
Lamb recorded seven catches (on 11 targets) for 58 yards during Sunday's 33-30 overtime loss to the Cardinals.
Ferguson suffered a low-ankle sprain during Sunday's loss to the Cardinals, Jeremy Fowler of ESPN reports.
Downs has been ruled out for the rest of Sunday's game against the Cardinals to be evaluated for a concussion, Jon Machota of The Athletic reports.
Ferguson (ankle) won't return to Sunday's game against the Cardinals, Joe Hoyt reports.
Ferguson suffered an ankle injury during Sunday's game against the Cardinals, Tommy Yarrish of the Cowboys' official site reports.
Locke (foot) is active for Sunday's game against the Cardinals.