San Francisco
| PASSING | CP/ATT | YD | TD | INT | FUML | FP | |
| B. Purdy | Brock Purdy | 16/28 | 192 | 1.20 | 0.97 | 0.02 | 14.13 |
| RUSHING | RUSH | YD | TD | YPC | FUML | FP | |
| C. McCaffrey | Christian McCaffrey | 14.8 | 72 | 0.36 | 4.9 | 0.19 | 14.38 |
| J. Mason | Jordan Mason | 5.3 | 31 | 0.11 | 5.8 | 0.05 | 3.63 |
| D. Samuel | Deebo Samuel | 3.2 | 19 | 0.17 | 5.9 | 0.11 | 9.18 |
| RECEIVING | REC | YD | TD | YPR | FUML | FP | |
| D. Samuel | Deebo Samuel | 3.9 | 51 | 0.21 | 13.2 | 0.11 | 9.18 |
| B. Aiyuk | Brandon Aiyuk | 3.8 | 50 | 0.29 | 13.0 | 0.04 | 6.9 |
| G. Kittle | George Kittle | 3.6 | 47 | 0.40 | 13.0 | 0.05 | 7.11 |
| C. McCaffrey | Christian McCaffrey | 4.4 | 38 | 0.25 | 8.6 | 0.19 | 14.38 |
| J. Jennings | Jauan Jennings | 1.9 | 23 | 0.10 | 11.9 | 0.02 | 2.85 |
| K. Juszczyk | Kyle Juszczyk | 1.2 | 12 | 0.07 | 10.1 | 0.02 | 2.17 |
| DEF-ST | SACK | INT | FREC | FGM | FGA | XP | |
| S. DST | SF DST | 2.82 | 0.78 | 0.91 | 1.3 | 1.5 | 1.9 |
PLAYERS LISTED AS OUT OR DOUBTFUL:Jimmy Garoppolo, Trey Lance, Elijah Mitchell, Ross Dwelley, Tyrion Davis-Price, Emmanuel Moseley, Jordan Matthews, Jason Verrett, Drake Jackson, Ambry Thomas, Maurice Hurst, Kalia Davis *Questionable players are included in the projection. | |||||||