New Orleans’ defensive debacle against San Francisco provided cause for concern. Now DE Marcus Davenport (foot) and DT Sheldon Rankins (knee) are finished for the season. Indianapolis should capitalize despite its own injury problems on offense, although top-tier WR T.Y. Hilton (calf) is on the verge of returning. The Colts have dropped five of six but four by one score.

The Saints have failed to cover their last three home games (1-2 SU) and are coming off a very emotional and physical game versus the 49ers. In that 48-46 loss, San Fran obliterated the Saints on the ground (6.8 yards per carry). The Saints just lost two key defensive linemen to injury. Indy could get T.Y. Hilton back, helping to open up the running game. Grab the points with a Colts team that's 11-2 ATS in its last 13 versus winning teams.

The Saints offense just lit up a great defense at home, and I don't see why they'll slow down against a solid but not great Colts unit here. Drew Brees looked excellent in that game, enough so that we can put worries of another late-season swoon to rest. Jacoby Brissett finally looked healthy last week, and I think he can lead the Colts offense to a nice point total, considering how well they do on third downs (No. 9 in NFL) and in the red zone (No. 7). Both these defenses just gave up 500-plus yards of offense in their last matchups, so why isn't this total higher?

The New Orleans defense was punched in the mouth last week against San Francisco. This week, it will welcome a Colts team that has struggled on offense the last couple of weeks. Right now, Indianapolis doesn’t have a significant run threat to take pressure off QB Jacoby Brissett. Look for the Saints to come out firing on all cylinders on Monday Night Football.