Garcia (elbow/neck/biceps) underwent thoracic outlet surgery Thursday and will miss the rest of the season, Arden Zwelling of Sportsnet.ca reports.
Means (Achilles) will begin a rehab assignment with High-A Quad Cities on Wednesday.
Mears (shoulder) was diagnosed with thoracic outlet syndrome Saturday and will undergo season-ending surgery, MLB.com reports.
Lukes went 2-for-4 with a two-run single during the Blue Jays' 5-3 loss to the Royals on Tuesday.
Miles will serve as the opening pitcher during Wednesday's game against the Royals, Mitch Bannon of The Athletic reports.
Lukes went 2-for-4 with a two-run single during the Blue Jays' 5-3 loss to the Royals on Tuesday.
Lugo (6-7) earned the win against the Blue Jays on Tuesday, allowing one run on six hits and one walk while striking out five across five innings.
Scherzer (1-7) took the loss against the Royals on Tuesday, allowing two runs on four hits and five walks while striking out four across five innings.
Massey was removed from Tuesday's game against the Blue Jays due to a head injury.
Gimenez (hamstring) is starting at shortstop and batting seventh Tuesday against the Royals.
