Ramirez went 1-for-3 with a two-run homer and a walk during Game 5 of the ALCS against the White Sox on Saturday.
Williams earned the win in Game 5 of the ALDS against the White Sox on Saturday, striking out 12 and allowing one hit and two walks across 5.2 scoreless innings.
Holderman will undergo season-ending surgery on his right wrist, Zack Meisel of The Athletic reports.
The Tigers optioned Hurter to the rookie-level Florida Complex League on Sunday.
Flaherty (forearm) was reinstated from the 15-day injured list Sunday and struck out one batter while allowing one hit and no walks over two scoreless innings in the Tigers' 4-2 loss to the Pirates in the season finale.
Valencia went 1-for-4 with a solo home run in Sunday's 4-2 loss to the Pirates.
Madden tossed three scoreless innings of relief with three strikeouts in Sunday's 4-2 loss to the Pirates.
McGonigle went 2-for-3 with a solo home run in Sunday's 4-2 loss to the Pirates.
Ryan (0-1) took the loss against the Pirates on Sunday, allowing two runs on three hits and two walks with three strikeouts over 1.1 innings.
Adell went 2-for-3 with a solo home run and a walk in Sunday's 3-2 loss to the Royals.
Detroit is six games under .500 in the second half of the season, barely holding onto the division lead at this point. The Guardians are one game back for the division and send out Gavin Williams who has been pitching very well, three earned runs, or less, in each of his last six starts. Cleveland got the victory in their last game against Tarik Skubal, who still may be dealing with tightness to his left side, but the value lies with the Guardians as Detroit is in danger of missing the playoffs, hitting .233 in September.
