Smith (3-3) allowed one earned run on two hits while striking out two across two innings to take the loss Wednesday against the Royas.
Teel went 1-for-3 with two RBI, a walk and a run scored Wednesday against the Royals.
Hader (4-2) took the loss Wednesday against the Mariners, allowing two runs (one earned) on two hits and four walks across 1.1 innings.
Pena (wrist) stole a base as a pinch runner in Wednesday's 6-5 extra-inning loss to the Mariners.
Diaz went 2-for-5 with a two-run home run and an RBI triple in Wednesday's 6-5 extra-inning loss to the Mariners.
Pecko allowed three runs on four hits and two walks while striking out two over 2.2 innings in a no-decision versus the Mariners on Wednesday.
Fedde took a no-decision against the Royals on Wednesday, allowing one run (none earned) on four hits and two walks in 2.2 relief innings. He struck out two.
The Astros placed Matthews on the 10-day injured list Wednesday with left knee inflammation, Chandler Rome of The Athletic reports.
Pena (wrist) isn't in the lineup for Wednesday's game against the Mariners, Brian McTaggart of MLB.com reports.
The Astros recalled Spence from Triple-A Sugar Land on Wednesday, Chandler Rome of The Athletic reports.
