ANALYSIS: Cal Quantrill has been solid but carries ... Join SportsLine for the pick!

ANALYSIS: I’m surprised to see this at -3.5, as is my model, which makes this game -6. Arizona QB Kyler Murray and WR DeAndre Hopkins looked spectacular and the Cardinals' offense is dangerous. If the Vikings had issues with Cincinnati in Week 1, imagine what could happen against Arizona.

ANALYSIS: I have this one at -4.9 and I’ll take the Saints to keep rolling against a Carolina team that allowed the New York Jets to make a solid comeback attempt late in the game in Week 1. New Orleans QB Jameis Winston looked capable while Panthers QB Sam Darnold had his issues. The Saints were able to bother Green Bay QB Aaron Rodgers enough in their opener, and I imagine they will give their division rivals some trouble too.

ANALYSIS: This one might scare people, but I go with my numbers. I have the Jets at +4 and think they’re getting a bit too much disrespect here. The Patriots showed vulnerability against Miami in Week 1, and I have them ranked quite close to Carolina, against whom the Jets would have covered in their season opener if given six points. Now New York plays at home, and I think they can keep this close enough.

ANALYSIS: I have this game being a close one, coming in at +1 for Philadelphia. The Eagles looked solid in their season opener, and we have the 49ers coming to the east coast for an early start. Take the points.