Iowa State has one of the best defense in country. They’re holding their opponents to eight points on the season a home. Three of their first four games have gone under 45 points and the Cyclones will win the defensive battle first then coast to a victory.

Honestly, if it's a Big 12 game that doesn't involve Houston, and has a double-digit spread, I'm not against taking the underdog blindly. As for this spot, Iowa State's off to a strong start, but regardless the Big 12 theory, I think the Cyclones are a little overvalued.