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Sat, Sep 287:30 pm UTCNotre Dame Stadium
69 F
Louisville
Cardinals
LVILLE
Last 5 ATS
W/L8-4
ATS6-6
O/U8-4-0
FINAL SCORE
24
-
31
Notre Dame
Fighting Irish
ND
Last 5 ATS
W/L11-1
ATS9-2
O/U7-5-0
SPREAD
MONEYLINE
OVER/UNDER
Last 5 ATS
8-4
Win /Loss
11-1
6-6
Spread
9-2
8-4-0
Over / Under
7-5-0
SPREAD
MONEYLINE
OVER/UNDER

Simulation Picks

SPREAD
LVILLE @ ND
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MONEYLINE
LVILLE @ ND
Subscribers Only

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OVER / UNDER
LVILLE @ ND
Subscribers Only

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49%
PUBLIC
51%
MONEY
5%
PUBLIC
95%
MONEY
Over70%
PUBLIC
Under30%
Over
MONEY
Under

Understanding Public and Money

Think of 'Public' as the percentage of people betting on each side and 'Money' as how much money is being bet. When there's a big difference between the 'Public' and 'Money' data, it usually means that the more serious bettors (referred to as 'Sharp Money') are favoring a particular side.

Expert Picks

Point SpreadNotre Dame -6.5 -118
WIN
Unit1.0
+1689
58-37 in Last 95 NCAAF Picks
+1545
51-32 in Last 83 NCAAF ATS Picks
+380
6-2 in Last 8 LVILLE ATS Picks
Mike's Analysis:

Notre Dame learned from its loss to Northern Illinois not to take anyone lightly. Louisville never should be, of course, but the Cardinals have staggered out of a starting three-game stretch with enough injuries to last a season and could be overlooked in some circumstances. The Fighting Irish are banged up, too, but wield more depth to handle most vacancies. Irish QB Riley Leonard has drawn brickbats for so-so downfield passing yet has proven to be a dangerous runner, an area the Cardinals were victimized recently.

Pick Made: Sep 28, 2:02 pm UTC on FanDuel
Money LineLouisville +205
LOSS
Unit1.0
+759
40-38 in Last 78 NCAAF Picks
+321
6-5 in Last 11 NCAAF ML Picks
Tom's Analysis:

There's too much value on the Cardinals here, seeing as how they might have the better QB in the matchup, and the more dynamic offense.

Pick Made: Sep 26, 5:17 pm UTC on Caesars
Over / UnderUnder 46.5 -110
LOSS
Unit1.0
+759
40-38 in Last 78 NCAAF Picks
+60
5-4 in Last 9 NCAAF O/U Picks
Tom's Analysis:

The further I dive into this matchup the louder I hear "I don't trust either of these offenses as much as the defenses" in the back of my mind. So if I don't trust either offense, there's only one logical choice.

Pick Made: Sep 26, 5:13 pm UTC on FanDuel
Over / UnderUnder 45.5 -110
LOSS
Unit1.0
+435
12-7 in Last 19 NCAAF Picks
+390
5-1 in Last 6 NCAAF O/U Picks
Chip's Analysis:

Both of these teams rank in the top-15 nationally in scoring defense each allowing less than 14.0 points per game. The Fighting Irish will also be looking to control this game on the ground, which will keep the clock running and limit possessions.

Pick Made: Sep 25, 2:43 pm UTC on FanDuel

Team Injuries

Louisville Cardinals
Saturday, Nov 29, 2025
Avatar
WR
Chris Bell
Undisclosed
Avatar
RB
Jamarice Wilder
Undisclosed
Avatar
RB
Keyjuan Brown
Undisclosed
Avatar
RB
Isaac Brown
Lower Leg
Avatar
RB
Duke Watson
Undisclosed
Saturday, Nov 22, 2025
Avatar
LB
Antonio Watts
Undisclosed
Avatar
QB
Travis Egan
Undisclosed
Avatar
RB
Shammai Gates
Undisclosed
Wednesday, Oct 01, 2025
Avatar
TE
Grant Houser
Knee
Notre Dame Fighting Irish
Sunday, Nov 30, 2025
Avatar
TE
Cooper Flanagan
Achilles
Monday, Nov 24, 2025
Avatar
LB
Kyngstonn Viliamu-Asa
Knee
Saturday, Nov 22, 2025
Avatar
K
Noah Burnette
Hip
Avatar
DL
Gabriel Rubio
Elbow
Avatar
OL
Billy Schrauth
Knee
Monday, Nov 17, 2025
Avatar
WR
Jaden Greathouse
Hamstring
Wednesday, Oct 15, 2025
Avatar
OL
Ashton Craig
Knee
Wednesday, Oct 01, 2025
Avatar
RB
Dylan Devezin
Shoulder
Avatar
RB
Kedren Young
Knee
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