Duke is coming off an ineffective game offensively as they lost by eighteen points against Florida State. They’ll face a Louisville team that is off extra rest after having a bye week. That combined with Duke’s Riley Leonard’s uncertainty has inflated this line slightly. Grab Duke plus the six.

Oft-injured Duke QB Riley Leonard appears poised to play. Ditto Louisville TB Jahwar Jordan, the ACC's second-leading rusher. The pair all but assures a good deal of scoring. Duke's defense is stout but the Ville is capable of big plays. The Cardinals are shaky in pass prevention, which should allow Leonard to find his spots. As an option, consider the Blue Devils and the points. If Leonard's fitness takes a turn for the worse, however, the Over still remains in play.