Simulation Picks
SPREAD
SF @ CHI
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MONEYLINE
SF @ CHI
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OVER / UNDER
SF @ CHI
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PUBLIC
MONEY
PUBLIC
MONEY
Over0%
PUBLIC
Under0%
Over
MONEY
Under
Understanding Public and Money
Think of 'Public' as the percentage of people betting on each side and 'Money' as how much money is being bet. When there's a big difference between the 'Public' and 'Money' data, it usually means that the more serious bettors (referred to as 'Sharp Money') are favoring a particular side.
Expert Picks
San Francisco -6.5 -110
LOSS
Unit1.0
+1249.5
64-48-5 in Last 117 NFL Picks
+460
10-5 in Last 15 NFL ATS Picks
Josh's Analysis:
There's a window of value on the 49ers at this reduced number. Trey Lance remains a question mark at QB, but he has some reliable help with the likes of Deebo Samuel and Elijah Mitchell. Justin Fields of Chicago isn't much more proven and he will struggle to throw downfield against the 49ers' pass rush. The Chicago defense will be serviceable but will miss centerpice Khalil Mack, who is now with the Chargers. Look for the 49ers to pull away late and clip this number.
Pick Made: Sep 11, 3:16 pm UTC on WHNJ
Team Injuries
San Francisco 49ers
Thursday, Dec 11, 2025

RB
Christian McCaffrey
IllnessQuestionable
Monday, Dec 01, 2025

LB
Tatum Bethune
AnkleQuestionable

DT
Sam Okuayinonu
AnkleQuestionable
Sunday, Nov 30, 2025

FB
Kyle Juszczyk
RibsQuestionable

LB
Nick Martin
ConcussionQuestionable
Chicago Bears
Friday, Dec 12, 2025

RB
Travis Homer
AnkleOut

CB
Kyler Gordon
GroinOut
Monday, Dec 08, 2025

WR
Rome Odunze
FootQuestionable
