Sore-ankled Carson Wentz never left the pocket once last Sunday. His mobility might be a tad improved, but pass protection will be compromised by the loss of All-Pro G Quentin Nelson, statistically the third-best pass blocker at his position — and the most durable, having never sat out a game. Already, the Colts have permitted eight sacks and 31 QB hits. Indy’s defense also has been inflicted by injury. Miami is missing QB Tua Tagovailoa, but backup Jacoby Brissett is a veteran who nearly mastered an upset of the Raiders, overtime winners on a buzzer-beating field goal.

I'm typically not looking to play against winless teams after we get a few weeks into the season as their lines tend to be inflated, but it's hard to stay away from fading a Colts team dealing with so many injuries. Carson Wentz may come into this one healthier than he was last week, but with multiple key offensive lineman injuries, I don't know that he'll exit the same way against a Dolphins defense that will be looking to get after the QB. Aside from at QB, the Dolphins are coming into this one pretty healthy, and I think their home-field advantage against a dome team could make a difference here. There are enough factors pulling me to Miami to lay it under 3.

While Carson Wentz wasn't one of them, a whopping seven Colts starters missed practice Thursday -- including three offensive linemen, led by All-Pro guard Quenton Nelson. Six of those seven were DNP for a second straight day, so that obviously does not bode well. Plus, Wentz is a statue these days with his sprained ankles. Miami is quite healthy other than QB Tua Tagovailoa remaining on IL (and Jacoby Brissett may be better regardless). This game could be ugly offensively, but I like Miami to win by at least a field goal.

The Dolphins are having major issues pushing the ball downfield, ranking next to last in the NFL in yards per play on offense. Jacoby Brissett needed 49 pass attempts to throw for 215 yards in Week 3. But on the other side, the Colts aren't having much success on offense either, managing just 4.6 yards per play on Sunday with a hobbled Carson Wentz despite facing a Tennessee defense that has largely gotten shredded this year. With two plodding offenses matching up, and with the Colts' best player dealing with an ankle sprain (Quenton Nelson), I think we have to look Under on a total that probably should be in the 40-41 range.