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Wed, Apr 031:40 am UTCPetco Park
61 F
St. Louis
Cardinals
STL
Last 5 ML
W/L83-79
ATS84-78
O/U74-83-5
FINAL SCORE
5
-
2
San Diego
Padres
SD
Last 5 ML
W/L93-69
ATS84-78
O/U82-76-4
SPREAD
MONEYLINE
OVER/UNDER
Last 5 ML
83-79
Win /Loss
93-69
84-78
Spread
84-78
74-83-5
Over / Under
82-76-4
SPREAD
MONEYLINE
OVER/UNDER

Simulation Picks

SPREAD
STL @ SD
Subscribers Only

Maximize Your Odds of Winning with SportsLine Model and Our Top-Rated Picks

MONEYLINE
STL @ SD
Subscribers Only

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OVER / UNDER
STL @ SD
Subscribers Only

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36%
PUBLIC
64%
MONEY
22%
PUBLIC
78%
MONEY
Over71%
PUBLIC
Under29%
Over
MONEY
Under

Understanding Public and Money

Think of 'Public' as the percentage of people betting on each side and 'Money' as how much money is being bet. When there's a big difference between the 'Public' and 'Money' data, it usually means that the more serious bettors (referred to as 'Sharp Money') are favoring a particular side.

Expert Picks

Money LineSan Diego -144
LOSS
Unit0.5
+1027.25
78-44 in Last 122 MLB ML Picks
+40.5
42-30 in Last 72 STL ML Picks
Matt's Analysis:

We always worry about Yu Darvish's wildness but he's usually much, much better at Petco Park and has looked pretty good overall in two starts this year, one at home. Miles Mikolas, meanwhile, was bombed in his opener at the Dodgers and regressed quite a bit in 2023. Nolan Gorman (27 HR last year) is out of the STL lineup. The Padres had just one runner in scoring position in Monday's loss, which is pretty hard to do. You know they want this W for ex-fired Cards manager Mike Shildt after that defeat.

Pick Made: Apr 03, 12:28 am UTC on FanDuel
Money LineSan Diego -134
LOSS
Unit1.0
Erik's Analysis:

Ideally I would play the Padres in the first five minutes but for this site that’s not an option. So I’ll take the clergy for the full game. Yu Darvish over Mikalos is the prime reason; Cards bullpen is a bit taxed helps too.

Pick Made: Apr 02, 4:28 pm UTC on FanDuel
Money LineSan Diego -135
LOSS
Unit1.0
+365
9-6 in Last 15 MLB Picks
+244
15-14 in Last 29 MLB ML Picks
Jason's Analysis:

The Cards opening day starter was awful in his first outing and I think we've seen the best of him. STL's alleged pitching upgrades don't do much for me and their bullpen is already taxed. Like the way the Pads have swung the lumber and I like Yu Darvish in this spot. Tough way for the Cards to open the season the West Coast. Seeing some quality arms

Pick Made: Apr 01, 11:24 pm UTC on DraftKings

Team Injuries

St. Louis Cardinals
Saturday, Mar 14, 2026
Avatar
C
Ivan Herrera
KneeQuestionable
Sunday, Mar 01, 2026
Avatar
SP
Hunter Dobbins
KneeQuestionable
Thursday, Feb 19, 2026
Avatar
CF
Lars Nootbaar
HeelOut
San Diego Padres
Friday, Mar 13, 2026
Avatar
2B
Will Wagner
ObliqueOut
Thursday, Mar 12, 2026
Avatar
SP
Joe Musgrove
ElbowQuestionable
Avatar
SP
Jhony Brito
ForearmIl
Avatar
RP
Bryan Hoeing
ElbowOut
Tuesday, Mar 10, 2026
Avatar
RP
Jason Adam
QuadricepsQuestionable
Tuesday, Mar 03, 2026
Avatar
SP
Griffin Canning
AchillesOut
Monday, Mar 02, 2026
Avatar
SP
Matt Waldron
Lower BodyOut
Thursday, Feb 26, 2026
Avatar
RP
Yuki Matsui
GroinQuestionable
Thursday, Feb 19, 2026
Avatar
SP
Yu Darvish
ElbowOut
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