We backed the Mariners in Joey Estes' MLB debut and he gave up five earned runs with three home runs allowed in that game. In his second start in the big leagues, I don't expect a whole lot to change. A struggling A's bullpen (without Mason Miller available) should also do him no favors after he exits the game. Pablo Lopez pitches for the Twins and says "All systems are go as normal" with this being his final start before the playoffs and I expect a full workload here. Lopez has been great in the second half of the season, posting a 3.20 ERA through 13 starts.

Pablo Lopez is 8-3 with a 2.79 ERA over his last 16 starts and is poised to hold down a weak Oakland lineup. A's rookie Joey Estes is making his second major-league start after giving up six runs (five earned) in 4.2 innings to the Mariners. Oakland has lost 10 of 12, with each of those defeats coming by at least two runs. The Twins won the series opener 11-3 and should cover the run line here.

The Twins won the first game of this series Tuesday by a score of 11-3. The Athletics have lost 10 of their last 12 games with all 10 of those defeats coming by at least two runs. They will start Joey Estes, who followed up his 5.23 ERA at Triple-A by allowing six runs over 4 2/3 innings in his big-league debut last week. The Twins will roll with Pablo Lopez, who has a 3.61 ERA and 1.15 WHIP. Look for the Twins to win this by multiple runs.