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Sat, Sep 064:00 pm UTCJack Trice Stadium
63 F
Iowa
Hawkeyes
IOWA
Last 5 ATS
W/L7-4
ATS8-3
O/U5-7-0
FINAL SCORE
13
-
16
Iowa State
Cyclones
IOWAST
Last 5 ATS
W/L8-4
ATS5-6
O/U4-8-0
SPREAD
MONEYLINE
OVER/UNDER
Last 5 ATS
7-4
Win /Loss
8-4
8-3
Spread
5-6
5-7-0
Over / Under
4-8-0
SPREAD
MONEYLINE
OVER/UNDER

Simulation Picks

SPREAD
IOWA @ IOWAST
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MONEYLINE
IOWA @ IOWAST
Subscribers Only

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OVER / UNDER
IOWA @ IOWAST
Subscribers Only

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49%
PUBLIC
51%
MONEY
9%
PUBLIC
91%
MONEY
Over26%
PUBLIC
Under74%
Over
MONEY
Under

Understanding Public and Money

Think of 'Public' as the percentage of people betting on each side and 'Money' as how much money is being bet. When there's a big difference between the 'Public' and 'Money' data, it usually means that the more serious bettors (referred to as 'Sharp Money') are favoring a particular side.

Expert Picks

SpreadIowa +3.5 -110
WIN
Unit1.0
+767
12-4 in Last 16 IOWA ATS Picks
Josh's Analysis:

The Hawkeyes have won 7 of the past 9 in this rivalry, though the Cyclones have managed wins in 2 of the past 3. However, Iowa State hasn't won at home in this series since 2011 and each of its past 5 wins against its in-state rival have come by 3 or fewer points. We'll grab the value-laden hook on the low key number and look for another tight, grinding affair.

Pick Made: Sep 05, 10:14 pm UTC on BetMGM
SpreadIowa +3.5 -110
WIN
Unit1.0
+440
6-3 in Last 9 NCAAF Picks
+170
4-3 in Last 7 NCAAF ATS Picks
Eric's Analysis:

Even though they beat Kansas State in Ireland, I wasn't overly impressed with what I saw from Iowa State in Week 0. As per most years, Iowa should be stronger on the lines of scrimmage and I'm bullish on their transfer QB, Mark Gronowski. I'll gladly take the 3.5 points and even pick the outright upset. Iowa 20, Iowa State 17.

Pick Made: Sep 05, 6:13 pm UTC on Caesars
Over/UnderOver 41.5 -105
LOSS
Unit1.0
+288
11-10 in Last 21 NCAAF Picks
Tom's Analysis:

Iowa's offense isn't as horrible as it looked last week against Albany. Not that it'll be good! Iowa State's defense has shown almost no ability to pressure opposing QBs to start the season and has allowed some explosive plays. I also think the Cyclones offense could pose matchup issues for the Hawkeyes' defense.

Pick Made: Sep 05, 1:39 am UTC on BetMGM
SpreadIowa +3.5 -115
WIN
Unit2.0
+442
9-6 in Last 15 NCAAF ATS Picks
Jeff's Analysis:

Rocco Becht hasn't thrown a pick in 84 attempts, but the Cyclones' win over Kansas State was misleading, as they were outgained by 70 yards in Week 0. Iowa played conservatively in its opener against Albany, passing for just 48 yards and relying on RB Xavier Williams, who rushed for 111 yards and a touchdown. They were saving their best plays for this matchup. Quarterback Mark Gronowski brings valuable experience to Iowa, collecting 49 wins, two national titles at South Dakota State, and the ability to run for first downs. Last year, Iowa's only home loss was against ISU, despite leading by 13 points. The Cyclones converted a 54-yard FG with 6 seconds remaining. With Iowa's strong lines of scrimmage, getting 3.5 points feels right.

Pick Made: Sep 04, 4:44 am UTC on BetMGM
Money LineIowa St. -142
WIN
Unit1.0
+183
6-3 in Last 9 NCAAF Picks
+130
3-1 in Last 4 IOWA ML Picks
Micah's Analysis:

Iowa only allowed 177 yards to Albany last week in a 34-7 win and debuted a new quarterback from South Dakota State, Mark Gronowski, but his stats look like every other Iowa quarterback, completing eight passes for 44 yards. Now they get Iowa State, who's already won and covered twice, and they've beaten Iowa twice in three years. Iowa only allowed 17 points per game last season, and that'll be right around what they allow this game, but their quarterback needs to show more to win against Iowa State. Maybe coach Kirk Ferentz is playing games by not showing off his quarterback in the first game, but it looked like every quarterback Ferentz has had in his 26 years as Iowa coach. Iowa State wins.

Pick Made: Sep 03, 5:28 pm UTC on DraftKings

Team Injuries

Iowa Hawkeyes
Saturday, Nov 29, 2025
Avatar
WR
Jarriett Buie
Undisclosed
Avatar
RB
Xavier Williams
Undisclosed
Saturday, Nov 22, 2025
Avatar
DB
TJ Hall
Undisclosed
Thursday, Oct 23, 2025
Avatar
TE
Addison Ostrenga
Achilles
Iowa State Cyclones
Saturday, Nov 29, 2025
Avatar
WR
Xavier Townsend
Undisclosed
Avatar
DB
Jamison Patton
Undisclosed
Wednesday, Nov 26, 2025
Avatar
OL
Trevor Buhr
Undisclosed
Tuesday, Nov 18, 2025
Avatar
TE
Gabe Burkle
Leg
Tuesday, Oct 28, 2025
Avatar
DB
Khijohnn Cummings-Coleman
Undisclosed
Sunday, Oct 12, 2025
Avatar
RB
Ryver Peppers
Undisclosed
Wednesday, Oct 01, 2025
Avatar
DB
Jeremiah Cooper
Undisclosed
Avatar
DB
Jontez Williams
Knee
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