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Sat, Nov 305:00 pm UTCMemorial Stadium
45 F
South Carolina
Gamecocks
SC
Last 5 ATS
W/L8-3
ATS9-3
O/U7-5-0
FINAL SCORE
17
-
14
Clemson
Tigers
CLEM
Last 5 ATS
W/L9-3
ATS6-7
O/U5-7-1
SPREAD
MONEYLINE
OVER/UNDER
Last 5 ATS
8-3
Win /Loss
9-3
9-3
Spread
6-7
7-5-0
Over / Under
5-7-1
SPREAD
MONEYLINE
OVER/UNDER

Simulation Picks

SPREAD
SC @ CLEM
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Maximize Your Odds of Winning with SportsLine Model and Our Top-Rated Picks

MONEYLINE
SC @ CLEM
Subscribers Only

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OVER / UNDER
SC @ CLEM
Subscribers Only

Maximize Your Odds of Winning with SportsLine Model and Our Top-Rated Picks

64%
PUBLIC
32%
MONEY
21%
PUBLIC
79%
MONEY
Over78%
PUBLIC
Under22%
Over
MONEY
Under

Understanding Public and Money

Think of 'Public' as the percentage of people betting on each side and 'Money' as how much money is being bet. When there's a big difference between the 'Public' and 'Money' data, it usually means that the more serious bettors (referred to as 'Sharp Money') are favoring a particular side.

Expert Picks

Money LineClemson -135
LOSS
Unit1.0
+216
20-18 in Last 38 NCAAF ML Picks
Josh's Analysis:

Perhaps never has this rivalry game had higher stakes, seeing as the winner could secure a bid in the 12-team playoff. The Tigers have been mostly solid, with a slip up against Louisville their lone blemish outside of a Week 1 loss to Georgia. The Gamecocks have their best team in ages and have won 5 straight, but Texas A&M is the lone notable opponent in that stretch. Let's back the program with the more proven pedigree to come through in this spot.

Pick Made: Nov 30, 4:26 pm UTC on DraftKings
Money LineSouth Carolina +115
WIN
Unit1.0
+529
22-19 in Last 41 NCAAF Picks
Gene's Analysis:

The Gamecocks are arguably playing the best ball in the SEC, having won five straight games by an average of 23.4 points per game. That includes two wins over ranked teams. South Carolina has been playing great defense all season, giving up just 18.2 points per game (14th in the country). Meanwhile, Clemson has not beaten a ranked team this season, and the Tigers' best win is a four-point victory against Pitt. Give me the Gamecocks on the money line.

Pick Made: Nov 30, 4:13 pm UTC on Caesars
Money LineClemson -135
LOSS
Unit2.0
+292
5-2 in Last 7 NCAAF Picks
Bob's Analysis:

Clemson is 3-3 ATS at home on the season. The Gamecocks come into this game riding a five-game win streak and have been holding their opponents to 265.3 total yards on the road. Clemson hasn’t played the toughest schedule this season, with their two strongest opponents being Georgia and Louisville, losing both games by double digits. The Tigers are 5-1 SU at home this season and still have enough firepower offense, averaging 525.8 yards at home.

Pick Made: Nov 30, 3:00 pm UTC on Caesars
Point SpreadClemson -2.5 -110
LOSS
Unit1.0
+649
14-7 in Last 21 NCAAF ATS Picks
+90
2-1 in Last 3 CLEM ATS Picks
Micah's Analysis:

Carolina has their eyes set on the Palmetto Bowl with hopes of beating Clemson and run their record to 9-3 and 9-3 against the spread. That's the thing I'm keying on is the spread. Clemson at home should at least be the 7-point favorite and they're only laying 3 or less. Clemson averages a 37-22 score on the season and their 469 yards per game is No. 6 in the nation. Clemson is 9-2, and they need to win any hopes of making the college football playoffs. I think that's a powerful incentive to win. Clemson covers.

Pick Made: Nov 29, 6:25 pm UTC on Caesars
Over / UnderOver 49 -110
LOSS
Unit1.5
+1441.5
78-58 in Last 136 NCAAF Picks
+640
26-17 in Last 43 NCAAF O/U Picks
+35
2-1 in Last 3 CLEM O/U Picks
Eric's Analysis:

Big stakes in this rivalry game as both teams have an outside chance at making the College Football Playoff with a win. No Tigers home game has seen less than 54 total points this season, which makes this line a bit puzzling. South Carolina is averaging more than 39 points per game during their current five game winning streak and their offense is just humming. Expect this to be one of the most fun games of the weekend and live up to the hype. The Gamecocks are 7-0 lifetime vs. the Tigers when both teams are ranked. Let the streak continue: South Carolina 34, Clemson 28.

Pick Made: Nov 26, 6:51 pm UTC on DraftKings

Team Injuries

South Carolina Gamecocks
No Player Injuries
Clemson Tigers
Saturday, Mar 28, 2026
Avatar
WR
T.J. Moore
Undisclosed
Wednesday, Mar 18, 2026
Avatar
RB
Jay Haynes
Quadriceps
Friday, Mar 06, 2026
Avatar
WR
Tristan Smith
Leg
Wednesday, Feb 25, 2026
Avatar
TE
Olsen Patt-Henry
Undisclosed
Thursday, Jan 15, 2026
Avatar
WR
Cole Turner
Lower Body
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