The 49ers’ string of player absentees reached an absurd conclusion when K Robbie Gould was placed on the COVID-19 inactive list on the day his contract extension was announced. San Francisco's injury list is almost as long as a grocery list. It closes a forgettable season - at "home" again in Arizona - against a motivated team whose defense is on fire. Seattle has allowed a league-low average of 13.7 points over its last five outings. The Seahawks have covered against the 49ers in 14 of their last 18 clashes.

Seattle's defense has stepped up in the second half while the offense has gone into a shell, and as a result, seven straight Seahawks games have gone Under. I think that defense will continue to have success against a beat-up 49ers offense that's down to its third QB. The 49ers were able to run all over Arizona in a win last week, but that's the strength of Seattle's defense. I can see the San Francisco defense putting together a big game in an attempt to play spoiler in what could be Robert Saleh's final game with the team. First team to 20 wins.

The Seattle defense has improved so much after the addition of healthy and fresh bodies to the lineup. Over their last six games, the Seahawks have allowed just 13.7 points a game. That's a significant improvement over their first six games when they allowed 29.6. The defense should shut down a 49ers offense that will be forced to start C.J. Beathard again at quarterback.