The Colts have lost six of their last seven games, and they've won by more than seven just once all season. Rookie Will Grier will make his first NFL start, but is that necessarily a bad thing for the Panthers (slumping Kyle Allen threw just 2 TDs and 5 INTs in Carolina's last two games). Take the points.

We will get to see a new QB in this game for the Panthers, as rookie Will Grier will get the start. He was taken in the third round of this year's draft. Unfortunately for him, he gets the start against one of the tougher defenses in football. The game will be a bumpy debut for the former West Virginia Mountaineer. The Colts cover.

Two words: Will Grier. The Carolina rookie QB, who has not so much taken a snap, likely will start as the Panthers, losers of six straight, play out the string. Though Indianapolis faces a short week, it should be eager to hit the field quickly and flush its Monday night whipping by the Saints. Colts WR T.Y. Hilton should be back in full swing after being limited Monday while returning from an injury layoff.