The White Sox are 4-13 in their last 17 road games and won't have Luis Robert for this matinee. Leadoff hitter Tim Anderson (.284 on-base percentage) continues to struggle. Cleveland's Cal Quantrill has turned his season around, posting a 2.77 ERA and 1.00 WHIP this month. Chicago's Michael Kopech is coming off a dominant performance, but he has struggled on the road (5.73 ERA) and in the daytime (6.41 ERA).

Chicago probably won't have its best hitter in Luis Robert as he left Tuesday's game with a hip issue, and with a day game after a night it would be pretty surprising if he's in there Wednesday. Sox pitcher Michael Kopech has been better of late overall but still has a 5.73 road ERA. Guards pitcher Cal Quantrill is 15-2 with a 3.05 ERA career at Progressive Field. Cleveland didn't use any of its high-leverage relievers in Tuesday's loss. Chicago used all three of its guys, which may or may not matter Wednesday.