The difference in this game should be the pitching matchup. Bieber has allowed just three runs in his two starts looking very good to start the season. Dallas Keuchel has struggled against this Guardians lineup, specifically Jose Ramirez and Amed Rosario. These two should produce a couple of runs early for the Guardians and with the pitching of Bieber, they should take Game 1 of the doubleheader.

Hate to fade my White Sox, but I have zero faith in Dallas Keuchel, and the Pale Hose lineup in Game 1 of the doubleheader looks rather watered-down with the likes of Gavin Sheets, Jake Burger, Adam Engel and Danny Mendick against Guards ace Shane Bieber -- who has owned the White Sox the past few years.