NFL DFS, 2025: Best FanDuel, DraftKings picks, lineup advice, player pool for Week 4 from a daily Fantasy pro

The 2025 NFL season continues Sunday with 13 games, but only 11 will be included on the main slate for many DFS sites since there's an early game in Dublin and then 'Sunday Night Football' in the evening. Eagles vs. Buccaneers and Chiefs vs. Ravens might be the most anticipated games, but daily Fantasy players will also have a close eye on Rams vs. Colts, which has the highest over/under on the slate at 49.5 and features potential NFL DFS picks such as Jonathan Taylor, Kyren Williams and Puka Nacua.

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW. 

Before making any Week 4 NFL DFS picks on sites like DraftKings and FanDuel, you NEED to hear what SportsLine daily Fantasy expert Mike McClure has to say.

McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends, and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings, including. In 2023, he finished tied for first in the DraftKings Millionaire Maker twice and the FanDuel Million once. Anyone who has followed him is way up!

We can tell you one of McClure's top NFL DFS picks for Sunday is Falcons receiver Drake London at $5,700 on DraftKings and $7,100 on FanDuel. Part of McClure's optimal NFL DFS strategy also includes rostering 49ers running back Christian McCaffrey at $8,500 on DraftKings and $9,300 on FanDuel.

McClure is also targeting an overlooked value player who could go off for MASSIVE numbers on Sunday! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who they are before locking in any lineups.

What are the top NFL DFS picks for Sunday, and which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW.