NBA DFS, 2025: Top FanDuel, DraftKings picks, lineups, advice for Wednesday, Dec. 10 from a daily Fantasy pro

The 2025 NBA Cup quarterfinals continue on Wednesday with Thunder vs. Suns at 7:30 p.m. ET and Lakers vs. Spurs at 10 p.m. ET. Thus, the NBA DFS player pool is limited with just two games, even with big names like Shai Gilgeous-Alexander, LeBron James, Luka Doncic and De'Aaron Fox in it. Meanwhile, Devin Booker (groin) is listed as questionable, so you'll want to monitor his status before inserting him into Wednesday NBA DFS lineups.

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Before making any NBA DFS picks on sites like DraftKings and FanDuel for this slate, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best NBA DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any NBA DFS player.

For this slate, one of McClure's top NBA DFS picks is Lakers point guard Luka Doncic at $12,000 on DraftKings and $12,400 on FanDuel. He's also rostering Spurs PG/SG Dylan Harper, ($4,700 on DraftKings, $5,100 on FanDuel), who scored a season-high of 22 points in his last game. The rookie has scored 15+ in four of his last five games, with at least 5 assists in four straight outings.

McClure is also targeting a player who could go off for massive numbers on Wednesday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

What are the top NBA DFS picks for Wednesday? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NBA DFS!

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