The Los Angeles Lakers visit the Cleveland Cavaliers for a cross-conference NBA matchup at 7 p.m. ET on Monday. Cleveland is favored by 5.5-points at home, while the Over-Under is set at 227 (see up-to-date odds for every game this week on our NBA odds page). Before making any Lakers vs. Cavaliers picks, you NEED to check out the NBA predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past three-plus seasons. The model enters Week 22 of the 2021-22 NBA season on a stunning 79-49 roll on all top-rated NBA picks, returning over $2,400. Anyone following it has seen HUGE returns.

The model knows the Cavaliers are fantastic on defense. Cleveland is No. 4 in the NBA in defensive efficiency, giving up only 1.07 points per possession. Opponents are shooting only 44.8 percent against the Cavaliers, including 51.0 percent on two-point attempts. Cleveland also leads the league in free throw prevention, yielding only 18.8 attempts per game. The Cavaliers round out the profile with top-10 marks in assists allowed and second-chance points allowed.

The model also knows the Lakers have strengths on both ends. Los Angeles is No. 7 in the NBA in two-point shooting at 54.0 percent, helping the team to shoot 46.5 percent overall. The Lakers are No. 5 in the league in fast break points, averaging 14.8 per game, and Los Angeles is in the top 10 in scoring 48.4 points in the paint per contest. On defense, havoc creation carries the day for the Lakers, with the team forcing 14.9 turnovers per game and generating top-eight marks in steals (7.8 per game) and blocks (5.5 per game).

Now, it has set its sights on Lakers vs. Cavaliers. We can tell you the model is leaning Under the total, and it also says one side of the spread hits in over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any NBA picks.

Who wins Lakers vs. Cavaliers? And which side of the spread hits in over 50 percent of simulations? ... Join SportsLine right now to find out which side of the Lakers vs. Cavaliers spread you should be all over Monday, all from the model on a roll on NBA picks!