A Big 12 battle is on tap between the No. 9 Kansas Jayhawks and the No. 15 Iowa State Cyclones at 8 p.m. ET on Tuesday at Allen Fieldhouse. The Jayhawks are 12-2 overall and 6-0 at home, while Iowa State is 13-2 overall and 1-1 on the road. Kansas is ranked fourth in the Big 12; Iowa State is ranked eighth. 

The Jayhawks are favored by 12.5 points in the latest Kansas vs. Iowa State odds from Caesars Sportsbook, while the over-under is set at 140. Before you make any Iowa State vs. Kansas picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Kansas vs. Iowa State 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Kansas vs. Iowa State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.