The No. 6 Houston Cougars and Towson Tigers will meet in the first round of the Charleston Classic, with the winner set to face the winner of Utah and Wake Forest. Tipoff is set for 6:30 p.m. ET on Thursday at TD Arena in Charleston. Houston is favored by 20.5 points in the latest Houston vs. Towson odds, while the over/under is set at 124.5 points via SportsLine consensus. 

Before entering any Towson vs. Houston picks, you NEED to see the college basketball predictions from the model at SportsLine.

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The model has simulated Houston vs. Towson 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

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