The Florida State Seminoles will face the Siena Saints in a Thanksgiving Day clash at the 2022 ESPN Events Invitational at Lake Buena Vista, Florida. It will be just the second-ever meeting between the schools. The Seminoles (1-4), who finished eighth in the Atlantic Coast Conference at 10-10 and were 17-14 overall in 2021-22, snapped a five-game losing streak dating back to last year with an 81-72 win over Mercer on Monday. The Saints (2-2), who placed third in the Metro Atlantic Athletic Conference at 12-8 and were 15-14 last season, have lost two in a row. Siena fell 69-59 at Harvard on Sunday.

The game from State Farm Field House tips off at 11 a.m. ET. Florida State is favored by 8.5 points at Caesars Sportsbook, while the over/under for total points is set at 140.5 (see up-to-date odds for every game this week on our college basketball odds page).

Before making any Florida State vs. Siena picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past six years, the proprietary computer model has generated more than $1,400 for $100 players on its top-rated college basketball picks against the spread. Anybody who has followed it has seen profitable returns!

The model knows the Seminoles have a good track record at the event, and have a 5-1 mark in their two previous appearances. Junior guard Darin Green Jr. leads the team in scoring, averaging 13.6 points per game, and is connecting on 44.4% of his field goals, including 50% from 3-point range, and is hitting on 83.3% of his free throws. He is also averaging 3.2 rebounds, 2.4 assists and one steal per game. His best game was a 24-point performance against Troy on Nov. 14. In that game, he also grabbed six rebounds and added two assists.

The model also knows sophomore guard Javian McCollum has had the hot hand for the Saints, scoring 20 points or more in three of the first four games. Despite being held to two points at Harvard on Sunday, McCollum is averaging 15.8 points, 4.5 assists, 2.3 rebounds and one steal per game. In an overtime loss to Army last Wednesday, he poured in 21 points, while dishing out five assists, grabbing three rebounds and making two steals. He has been red hot from the floor, connecting on 50% of his field goals, including 41.2% from 3-point range and 81.8% from the free throw line.

Now, it has set its sights on Florida State vs. Siena. It is leaning Over on the total and it has also generated an against-the-spread pick that cashes in well over 60% of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Florida State vs. Siena? And which side of the spread hits in well over 60% of simulations? ... Join SportsLine right now to find out which side of the Florida State vs. Siena spread you should be all over Thursday, all from the model on a roll on college basketball picks!