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Sat, Sep 217:30 pm UTCMichigan Stadium
80 F
USC
Trojans
USC
Last 5 ATS
W/L5-6
ATS7-5
O/U5-6-1
FINAL SCORE
24
-
27
Michigan
Wolverines
MICH
Last 5 ATS
W/L7-5
ATS5-7
O/U7-5-0
SPREAD
MONEYLINE
OVER/UNDER
Last 5 ATS
5-6
Win /Loss
7-5
7-5
Spread
5-7
5-6-1
Over / Under
7-5-0
SPREAD
MONEYLINE
OVER/UNDER

Simulation Picks

SPREAD
USC @ MICH
Subscribers Only

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MONEYLINE
USC @ MICH
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OVER / UNDER
USC @ MICH
Subscribers Only

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67%
PUBLIC
33%
MONEY
88%
PUBLIC
12%
MONEY
Over72%
PUBLIC
Under28%
Over
MONEY
Under

Understanding Public and Money

Think of 'Public' as the percentage of people betting on each side and 'Money' as how much money is being bet. When there's a big difference between the 'Public' and 'Money' data, it usually means that the more serious bettors (referred to as 'Sharp Money') are favoring a particular side.

Expert Picks

Point SpreadUSC -4 -110
LOSS
Unit2.0
+55
4-2 in Last 6 NCAAF ATS Picks
+214
4-2 in Last 6 MICH ATS Picks
Jimmie's Analysis:

Michigan has been home underdogs in two of the last three weeks, which is kind of wild honestly. This number keeps getting bet down, and I can't really figure out why. USC has blown me away with its defensive turnaround this season, and I believe they still have the talent to resemble a typical Lincoln Riley offense. Alex Orji could be an X-factor, but USC has the speed on defense to contain him. The Trojans have had two weeks to prepare for this matchup, and I think it'll show. All due respect to Michigan, but I have USC winning by 10+ here.

Pick Made: Sep 21, 4:48 pm UTC on Caesars
Point SpreadUSC -4 -115
LOSS
Unit1.0
+1689
58-37 in Last 95 NCAAF Picks
+1545
51-32 in Last 83 NCAAF ATS Picks
+718
15-7 in Last 22 MICH ATS Picks
Mike's Analysis:

This is not your grandmother's Michigan team. Nor it is last year's, which won the CFP title. The Wolverines already have switched QBs, with replacement Alex Orji having thrown all of seven passes in three college seasons. The reborn USC defense should handle him with ease. For the Trojans, offense is a given, and it could feast on the Wolves' vulnerable pass D. A bye week makes the Trojans fresh, and their Big Ten debut raises the excitement level.

Pick Made: Sep 21, 4:32 pm UTC on Caesars
Point SpreadUSC -4 -110
LOSS
Unit1.0
+529
22-19 in Last 41 NCAAF Picks
+470
5-1 in Last 6 NCAAF ATS Picks
+185
3-2 in Last 5 MICH ATS Picks
Gene's Analysis:

This line opened at -6.5 earlier in the week, but the number has dropped to a point that makes USC attractive. The Wolverines remain a mess offensively and on Saturday will start Alex Orji, who was beaten out by Davis Warren prior to the season. I like the Trojans improved defense to keep Michigan bottled up. Meanwhile, USC will have the best quarterback on the field in Miller Moss, who already has been clutch this season in beating LSU. Also, the Trojans had an off week last week, giving them an extra seven days to prepare for this. Give me USC.

Pick Made: Sep 21, 9:05 am UTC on Caesars
Over / UnderUnder 44.5 -120
LOSS
Unit1.0
+759
40-38 in Last 78 NCAAF Picks
+60
5-4 in Last 9 NCAAF O/U Picks
Tom's Analysis:

With the change to Alex Orji at QB, Michigan should be more run-heavy than usual, and look to control the game. As good as USC has looked, this is the first time Miller Moss has faced a good defense in a hostile environment, so I expect the Trojans offense to have trouble too.

Pick Made: Sep 20, 7:00 pm UTC on FanDuel
Point SpreadUSC -5.5 -110
LOSS
Unit1.0
+991
45-32 in Last 77 NCAAF ATS Picks
Emory's Analysis:

With how the offense has looked so far this season, it is save to say that the Trojans should be able to find points against Michigan. Defensively, look for the Trojans to pester Michigan QB Alex Orji throughout the ball game, keeping their offense searching for answers.

Pick Made: Sep 18, 1:26 pm UTC on Caesars
Over / UnderUnder 46.5 -110
LOSS
Unit1.0
+1441.5
78-58 in Last 136 NCAAF Picks
+640
26-17 in Last 43 NCAAF O/U Picks
Eric's Analysis:

I just don't trust the Wolverines to be able to score more than twice. Then again, picking the under in a Lincoln Riley-coached game, especially in the 40s, is a very scary proposition. But the Trojans' defense looks to be vastly improved under new coordinator D'Anton Lynn and I don't see Michigan scoring more than two touchdowns, nor giving up more than four. USC 23, Michigan 17.

Pick Made: Sep 17, 10:28 pm UTC on DraftKings

Team Injuries

USC Trojans
Tuesday, Dec 02, 2025
Avatar
RB
Bryan Jackson
Transfer Portal
Sunday, Nov 30, 2025
Avatar
LB
Anthony Beavers Jr.
Undisclosed
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CB
Prophet Brown
Undisclosed
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OL
Kilian O'Connor
Undisclosed
Avatar
S
Bishop Fitzgerald
Undisclosed
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RB
Waymond Jordan
Ankle
Friday, Nov 28, 2025
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OL
Elijah Paige
Knee
Saturday, Nov 22, 2025
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S
Kamari Ramsey
Undisclosed
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K
Caden Chittenden
Hamstring
Thursday, Nov 06, 2025
Avatar
DT
Jamaal Jarrett
Undisclosed
Monday, Oct 13, 2025
Avatar
RB
Eli Sanders
Knee
Wednesday, Oct 01, 2025
Avatar
CB
Chasen Johnson
Knee
Michigan Wolverines
Saturday, Nov 29, 2025
Avatar
TE
Max Bredeson
Foot
Avatar
DB
Rod Moore
Undisclosed
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LB
Ernest Hausmann
Undisclosed
Avatar
RB
Justice Haynes
Foot
Avatar
WR
Semaj Morgan
Undisclosed
Avatar
TE
Hogan Hansen
Undisclosed
Saturday, Nov 22, 2025
Avatar
OL
Evan Link
Knee
Saturday, Nov 15, 2025
Avatar
LB
Devon Baxter
Undisclosed
Saturday, Oct 11, 2025
Avatar
RB
Donovan Johnson
Undisclosed
Saturday, Oct 04, 2025
Avatar
WR
C.J. Charleston
Undisclosed
Avatar
LB
Jaydon Hood
Undisclosed
Avatar
OL
Andrew Babalola
Undisclosed
Avatar
WR
I'Marion Stewart
Undisclosed
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