Syracuse averages 247.7 rushing yards per game, No. 3 in the nation. Chains keep moving, clock runs and the typical Orange score is 29-22. They’ve had a week off but won their previous two games and have covered seven straight. Louisville has lost four of its last five. Syracuse has a much better defense as well.

The Orange had this game circled ever since the schedule was released. Syracuse lost 30-0 in Louisville last season. In a schedule quirk, the Orange now return to the same venue with extra prep time, in hopes of becoming bowl-eligible. Syracuse is one of the most improved teams across the board. The Orange own a +1.3 net yard differential, while Louisville owns a +0.7. Syracuse owns the better offensive line, defensive line and overall defense. Look for the Orange to win outright and improve to 9-1 ATS this season.