Florida State Seminoles vs. Clemson Tigers Odds, Betting Lines, Expert picks, Game Projections, DFS Projections and Player Prop Projections - Saturday 02/21 12:00 PM ET - SportsLine.com

Sat, Feb 2112:00 pm ETLittlejohn Coliseum

trackSeminoles @ Tigers on CBS Sports

Florida State

Seminoles

FSU

Last 5 ATS

W/L15-14

ATS17-14

O/U15-16-0

FINAL SCORE

70

-

65

Clemson

Tigers

CLEM

Last 5 ATS

W/L19-9

ATS15-15

O/U13-18-0

Last 5 ATS

15-14

Win /Loss

19-9

17-14

Spread

15-15

15-16-0

Over / Under

13-18-0

SPREAD

MONEYLINE

OVER/UNDER

OPPONENT	W/L	ATS	ML	O/U
SMU03/07/2026	78-91WIN	-1.5WIN	-123WIN	159.5OVER
@PITT03/04/2026	75-74WIN	-1.5LOSS	-133WIN	144.5OVER
@GATECH02/28/2026	80-71WIN	-5.5WIN	-254WIN	158.5UNDER
MIAMI02/24/2026	83-73LOSS	+2.5LOSS	+116LOSS	153.5OVER
@CLEM02/21/2026	70-65WIN	+8.5WIN	+334WIN	145.5UNDER

Florida State Seminoles vs. Clemson Tigers Odds, Betting Lines, Expert picks, Game Projections, DFS Projections and Player Prop Projections - Saturday 02/21 12:00 PM ET - SportsLine.com