Colts vs Cardinals prediction, odds, props, point spread: NFL expert makes Christmas Day player prop bet picks

Jonathan Taylor, Carson Wentz and the Indianapolis Colts (8-6) look to keep their division title hopes alive when they hit the road to take on Kyler Murray and the Arizona Cardinals (10-4) in a pivotal Week 16 NFL matchup on Christmas night. Kickoff is at 8:15 p.m. ET from State Farm Stadium in Glendale, Ariz.. The Cardinals are two-point favorites in the latest Colts vs. Cardinals odds from Caesars Sportsbook. The over-under is set at 49 points. All-Pro guard Quenton Nelson (COVID) is out for Indianapolis, while J.J Watt (shoulder) and DeAndre Hopkins (knee) remain out for Arizona. In addition to the standard Cardinals vs. Colts point spread and Christmas Day NFL betting lines, Caesars is also offering a plethora of prop bet options for this prime time matchup, and SportsLine NFL expert R.J. White has just revealed his top player prop plays.

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White, a CBS Sports fantasy and gambling editor, ended the 2020 season on an 80-59 run on all NFL picks, returning more than $1,400 during that span. He also enters Week 16 as SportsLine's No. 5 rated NFL expert, going 17-8 (+810) on his last 25 NFL ATS picks. It's no surprise, as White has cashed huge twice in the world's most prestigious football handicapping competition, the Las Vegas SuperContest. Anyone who has followed his picks has seen HUGE returns.

You can see all of White's expert NFL picks and analysis HERE.

Now, White has locked in on Colts vs. Cardinals and just revealed his top three prop bet picks for this Week 16 Christmas Day NFL matchup. He has two confident prop bet picks featuring quarterbacks Kyler Murray and Carson Wentz. He's also made a bold call predicting a big night for a Pro Bowler for the Cardinals. You absolutely need to see all of White's NFL Week 16 Christmas Day prop bet picks before locking in any bets of your own.

So which NFL prop bets should you back on Christmas Day? And which Kyler Murray and Carson Wentz prop bets should you be all over in Week 16? ... Join SportsLine now to find out, all from the NFL expert who has cashed huge twice in the world's most prestigious football handicapping competition, the Las Vegas SuperContest!

Kyler Murray Over 1.5 passing TDs (-130)

"Murray is coming off possibly his worst game of the season against one of the worst teams in the league, but I think this is a great spot for him to bounce back and throw a couple touchdowns. The Colts have trouble stopping opposing passing games and are tied for the most passing touchdowns allowed to QBs in the league. Murray may be without running back James Conner, and even if he does play he's not going to be close to 100%. That should mean more passing in the red zone against a Colts team that ranks 28th in red zone percentage on defense. There's also the possibility the Cardinals fall behind against one of the league's better teams and Murray is throwing more than he typically would, which happened in each of his last two games even if the touchdowns weren't there."

Zach Ertz Over 4.5 receptions (+110)

"Ertz has been a target machine over the last two weeks, catching five passes on seven targets against the Rams and then six passes on 11 targets in the loss to the Lions. Kyler Murray should continue to look heavily in his direction with DeAndre Hopkins sidelined, and this is a great matchup for Ertz to shine. The Colts give up the most receiving yards and second-most receptions to tight ends in the league, and they just gave up 77 yards on six receptions to Hunter Henry, with two of those going for touchdowns. Ertz's snap share was higher last week than it's been all season with Hopkins sidelined, and if he's on the field nearly 90% of the time, odds are he's getting to five receptions for a third straight game."

Carson Wentz Longest completion Under 34.5 yards (-120)

"Wentz hasn't had to do much in the passing game since mid-November with the Colts winning most of their games, topping 200 yards just once in his last five games. He's thrown a 35-yard completion just once since the end of October, which is pretty incredible for a quarterback who has played nearly every snap during that stretch. His longest completion in the month of December? Just 24 yards to Nyheim Hines. He's up against a defense that's allowed 10 passes of 35 yards or more this season, but four came from Matthew Stafford and another two from Russell Wilson to Tyler Lockett. Against Wentz, I think they'll be able to shut down any long pass attempts and keep us under this number."

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