Vasquez will start Sunday's matchup against the Astros on Sunday, Jeff Sanders of The San Diego Union-Tribune reports.
Kepler isn't in the lineup for Saturday's game against the Dodgers.
Tatis went 2-for-5 with a solo home run Friday in a loss to the Astros.
Ray (10-7) allowed four runs on seven hits and five walks while striking out two over five innings in Friday's 6-3 loss to the Astros. He also tossed two wild pitches.
The Padres announced Friday that Andujar no longer requires a splint for his fractured right wrist and has been cleared for light activity, MLB.com reports.
Musgrove (elbow) struck out three and allowed one earned run on two hits and two walks across 2.2 innings in a rehab start Tuesday at Single-A Lake Elsinore.
Lawlar (hamstring) could have his rehab moved to Triple-A Reno next week, MLB.com reports.
Soroka (glute) is expected to start Monday against the Rockies, MLB.com reports.
Arenado went 1-for-4 with a solo home run in Friday's 4-3 win over the Dodgers.
Tawa went 1-for-3 with a walk, a stolen base and a run scored in Friday's 4-3 win over the Dodgers.
