I'll bite on the Padres run line here. Luis Cessa's 9.55 ERA is inflated from his 11-run outing against the Phillies, but he's still just 1-3 this season. The Padres counter with Seth Lugo, who has been solid with the exception of his most recent outing. San Diego won the first game of this series 8-3, but lost yesterday's low-scoring game 2-1. I think the Padres bounce back in this day game. Take the home team on the run line.

The Reds are big underdogs again Wednesday, but this time they're at a significant pitching disadvantage. Cincinnati starter Luis Cessa enters with a 9.55 ERA, a 2.22 WHIP and a hard-hit rate of 47.8 percent. San Diego's Seth Lugo has made a smooth transition to the starting rotation and owns a 1.04 career ERA in 14 appearances against the Reds. Play the Padres -- who had won seven straight over Cincinnati until Tuesday's extra-inning loss -- on the run line.