Orioles should have the edge in every aspect of this game. Their starter, Cole Irvin, was with the A's the last two season so he should be very familiar with this lineup. The A's are 4-16 when Adam Oller pitches over the last two seasons. In one career start against the Orioles, Oller went five innings allowing six runs, including four home runs. Orioles won that game 8-1. Take the Orioles to win this game by multiple runs.