Virginia vs. Louisville odds, line, spread: Proven model reveals college basketball picks, predictions for Mar 9, 2022

Virginia makes its debut in the ACC basketball tournament on Wednesday against Louisville, which won its tourney-opener on Tuesday. The Cavaliers won two games against the Cardinals earlier this season, including the regular season finale last Saturday, 71-61. Louisville finished the regular season 14-18 and lost 11 of its last 12 games, and Virginia ended things 18-12.

Tip-off from the Barclays Center in Brooklyn, New York, is set for 9:30 p.m. ET. The Cavaliers are favored by six points in the latest Virginia vs. Louisville odds from Caesars Sportsbook, and the over-under is set at 122.5. Before you make any Louisville vs. Virginia picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $1,600 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Virginia vs. Louisville 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

Who wins Virginia vs. Louisville? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks ... If you're already a member, see the picks below!