UFC 322 odds, picks: MMA analyst releases picks for Della Maddalena vs. Makhachev and other fights for November 15 fight

Welterweight champion Jack Della Maddalena takes on former lightweight king Islam Makhachev in the main event of UFC 322 on Saturday night. The main card is set for 10 p.m. Et from Madison Square Garden.

Makhachev is a -298 favorite (risk $298 to win $100), while Della Maddalena is priced at +240 (risk $100 to win $240) in the latest MMA odds for UFC 322: Della Maddalena vs. Makhachev. 

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Before making any UFC 322 picks, make sure you see the MMA predictions and betting advice from SportsLine expert Daniel Vithlani. 

Vithlani is a highly analytical UFC bettor who has been a consistent winner for SportsLine members since making his debut in January 2023 with a 5-0 record for UFC 283. In fact, he's up over $1,500 on his UFC main card picks!

His other highlights include calling an upset for Sean O'Malley (+210) against Aljamain Sterling (-250) at UFC 292 as part of a 4-1 main card, and his UFC 299 winners included underdog selections on Dustin Poirier (+190) against Benoit Saint Denis (-230) and Michael Page (+110) against Kevin Holland (-130). Anyone who has followed him could be way up.

This week at UFC 322: Della Maddalena vs. Makhachev, Vithlani is backing Chepe Mariscal (-102) to pull a small upset against Pat Sabbatini (-118) in a featherweight matchup on the early preliminary card.

He's also backing a fighter whose "constant barrage of strikes and takedowns" will lead to a MASSIVE victory! You ABSOLUTELY need to see his UFC Fight Night picks before making any of your own!

Who wins Della Maddalena vs. Makhachev, and which fighter is a MUST-BACK? Join SportsLine now to see which fighters you need to be all over, all from the expert who profited more than $1,500 on UFC main-card picks!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW.